ID E0Z4N1_9THEO Unreviewed; 256 AA.
AC E0Z4N1;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=Protein RecA {ECO:0000256|ARBA:ARBA00015553, ECO:0000256|RuleBase:RU000526};
DE AltName: Full=Recombinase A {ECO:0000256|RuleBase:RU000526};
DE Flags: Fragment;
GN Name=recA {ECO:0000313|EMBL:ADM45089.1};
OS Thermoanaerobacter uzonensis.
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacter.
OX NCBI_TaxID=447593 {ECO:0000313|EMBL:ADM45089.1};
RN [1] {ECO:0000313|EMBL:ADM45089.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JW/IW_A615_35_2 {ECO:0000313|EMBL:ADM45142.1}, JW/IW_B621_3
RC {ECO:0000313|EMBL:ADM45092.1}, JW/IW_J614_4
RC {ECO:0000313|EMBL:ADM45089.1}, JW/IW_J614_60
RC {ECO:0000313|EMBL:ADM45091.1}, JW/IW_V634_3
RC {ECO:0000313|EMBL:ADM45090.1}, JW/IW_V634_81
RC {ECO:0000313|EMBL:ADM45143.1}, and JW/IW_V634_82
RC {ECO:0000313|EMBL:ADM45094.1};
RA Wagner I.D., Varghese L., Wiegel J.;
RT "Universally conserved protein coding gene sequence heterogeneity among
RT Thermoanaerobacter uzonensis isolates from geothermal springs of Kamchatka,
RT Russian Far East.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC DNA, and the ATP-dependent hybridization of homologous single-stranded
CC DNAs. {ECO:0000256|RuleBase:RU000526}.
CC -!- SIMILARITY: Belongs to the RecA family. {ECO:0000256|ARBA:ARBA00009391,
CC ECO:0000256|RuleBase:RU004527}.
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DR EMBL; HM190869; ADM45089.1; -; Genomic_DNA.
DR EMBL; HM190870; ADM45090.1; -; Genomic_DNA.
DR EMBL; HM190871; ADM45091.1; -; Genomic_DNA.
DR EMBL; HM190872; ADM45092.1; -; Genomic_DNA.
DR EMBL; HM190874; ADM45094.1; -; Genomic_DNA.
DR EMBL; HM190922; ADM45142.1; -; Genomic_DNA.
DR EMBL; HM190923; ADM45143.1; -; Genomic_DNA.
DR AlphaFoldDB; E0Z4N1; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd00983; RecA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013765; DNA_recomb/repair_RecA.
DR InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049428; RecA-like_N.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR NCBIfam; TIGR02012; tigrfam_recA; 1.
DR PANTHER; PTHR45900:SF1; MITOCHONDRIAL DNA REPAIR PROTEIN RECA HOMOLOG-RELATED; 1.
DR PANTHER; PTHR45900; RECA; 1.
DR Pfam; PF00154; RecA; 1.
DR PRINTS; PR00142; RECA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00321; RECA_1; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004527};
KW DNA damage {ECO:0000256|RuleBase:RU004527};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172,
KW ECO:0000256|RuleBase:RU004527}; DNA repair {ECO:0000256|RuleBase:RU000526};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004527};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004527};
KW SOS response {ECO:0000256|RuleBase:RU000526}.
FT DOMAIN 9..168
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
FT DOMAIN 173..246
FT /note="RecA family profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50163"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADM45089.1"
FT NON_TER 256
FT /evidence="ECO:0000313|EMBL:ADM45089.1"
SQ SEQUENCE 256 AA; 27179 MW; 3575B82B03B5956E CRC64;
RLGDTAKLNV EVIPTGSLEL DIALGVGGVP RGRIIEIFGP ESSGKTTLAL HMIAEAQKMG
GTGAFIDAEH ALDPVYAKNL GVNIEDLLVA QPDTGEQALE IAEALVRSGA VDIIVIDSVA
ALVPKAEIDG EMGDSHVGLQ ARLMSQALRK LAGVTSKSKT IVVFINQLRE KVGVMFGNPE
TTPGGRALKF YATIRLDVRK IDAIKQGNEI IGSRTRVKVV KNKIAPPFKQ AEFDIMYGEG
ISREGSILDI GASIDI
//
