ID E0ZQM3_9HYPO Unreviewed; 536 AA.
AC E0ZQM3;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 08-NOV-2023, entry version 36.
DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418};
DE EC=2.7.7.6 {ECO:0000256|ARBA:ARBA00012418};
DE Flags: Fragment;
GN Name=RPB1 {ECO:0000313|EMBL:ADM86616.1};
OS Fusarium breve.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium solani species complex.
OX NCBI_TaxID=2747387 {ECO:0000313|EMBL:ADM86616.1};
RN [1] {ECO:0000313|EMBL:ADM86616.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRRL 28009 {ECO:0000313|EMBL:ADM86616.1};
RX PubMed=20686083; DOI=10.1128/JCM.00989-10;
RA O'Donnell K., Sutton D.A., Rinaldi M.G., Sarver B.A., Balajee S.A.,
RA Schroers H.J., Summerbell R.C., Robert V.A., Crous P.W., Zhang N., Aoki T.,
RA Jung K., Park J., Lee Y.H., Kang S., Park B., Geiser D.M.;
RT "Internet-accessible DNA sequence database for identifying fusaria from
RT human and animal infections.";
RL J. Clin. Microbiol. 48:3708-3718(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550};
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DR EMBL; HM347149; ADM86616.1; -; Genomic_DNA.
DR AlphaFoldDB; E0ZQM3; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR007075; RNA_pol_Rpb1_6.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000313|EMBL:ADM86616.1};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..131
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04983"
FT DOMAIN 160..262
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF05000"
FT DOMAIN 269..536
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04998"
FT DOMAIN 335..519
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04992"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADM86616.1"
FT NON_TER 536
FT /evidence="ECO:0000313|EMBL:ADM86616.1"
SQ SEQUENCE 536 AA; 59460 MW; 41386A09A7A95EC5 CRC64;
TFLTKEQIMN SMLWVPNWDG VIPQPAILKP RPRWTGKQLI SMVIPKEVTL HNGTDKKEDA
PLKDEGILIQ AGQLMYGLPT KKIVGAAAGG IVHISYNELG AEGAMAFLNG VQQVVTYWLL
NNGHSIGIGD TIPDKATIEK VQVHIDEEKA EVARLTAMAT ANELEALPGM NVRATFENKV
SMALNQARDK AGTTTQKSLK DSNNAVTMAS SGSKGSSINI SQMTALVGQQ IVEGKRIPFG
FKYRTLPHFT KDDYSPEARG FVENSYLRGL TPSEFFFHAM AGREGLIDTA VKTAETGYIQ
RRLVKALEDL SARYDGTVRN SLGDVVQFLY GEDGLDAMCI EKQKLGILNM SNAAFKAKYR
LDLANPPEWF KSDYEFGNEL TGDRPSMALL DTEWEALLKD RRVIRQINKA KMNEEMMQLP
LNITRIIESA KRVFNVKAND RSNLRPSDVI PSVQNLLDHM KIVRGTDPIS VEADANATIL
FKGLLRSRLA FKEVVKEHRL NKLAFDHVIG ELQNRWDRAF VSPGEMVGVL AAQSIG
//
