ID E1B9M8_BOVIN Unreviewed; 838 AA.
AC E1B9M8;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 3.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Scavenger receptor class F member 2 {ECO:0000313|Ensembl:ENSBTAP00000025815.6};
GN Name=SCARF2 {ECO:0000313|Ensembl:ENSBTAP00000025815.6,
GN ECO:0000313|VGNC:VGNC:34327};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000025815.6, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000025815.6, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000025815.6,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000025815.6}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000025815.6};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_002694730.1; XM_002694684.3.
DR RefSeq; XP_606519.4; XM_606519.6.
DR AlphaFoldDB; E1B9M8; -.
DR SMR; E1B9M8; -.
DR STRING; 9913.ENSBTAP00000025815; -.
DR PaxDb; 9913-ENSBTAP00000025815; -.
DR Ensembl; ENSBTAT00000025815.6; ENSBTAP00000025815.6; ENSBTAG00000019375.6.
DR GeneID; 528108; -.
DR KEGG; bta:528108; -.
DR CTD; 91179; -.
DR VEuPathDB; HostDB:ENSBTAG00000019375; -.
DR VGNC; VGNC:34327; SCARF2.
DR eggNOG; KOG1218; Eukaryota.
DR GeneTree; ENSGT00950000183101; -.
DR HOGENOM; CLU_017821_1_0_1; -.
DR InParanoid; E1B9M8; -.
DR OMA; KCTCHPN; -.
DR TreeFam; TF332598; -.
DR Proteomes; UP000009136; Chromosome 17.
DR Bgee; ENSBTAG00000019375; Expressed in uterine cervix and 100 other cell types or tissues.
DR GO; GO:0005044; F:scavenger receptor activity; IBA:GO_Central.
DR GO; GO:0007157; P:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; IBA:GO_Central.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 2.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR042635; MEGF10/SREC1/2-like.
DR PANTHER; PTHR24043; SCAVENGER RECEPTOR CLASS F; 1.
DR PANTHER; PTHR24043:SF5; SCAVENGER RECEPTOR CLASS F MEMBER 2; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 7.
DR SMART; SM00180; EGF_Lam; 6.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00022; EGF_1; 4.
DR PROSITE; PS50026; EGF_3; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 37..838
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018770598"
FT DOMAIN 64..103
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 229..263
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 558..838
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..791
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 93..102
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 253..262
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 838 AA; 88136 MW; D0541ED20293E7D9 CRC64;
MEGAGPRGAG PARRRGAGGP SLLLLLLWLL PGPTAPQELS PRGRNVCRAP GSQELTCCAG
WRQQGDECGI AVCEGNSTCS ENEVCVRPGE CRCRHGYFGA NCDTKCPRQF WGPDCKELCV
CHPHGQCEDV TGQCTCHARR WGARCEHACQ CQHGACHPRS GACRCEPGWW GPQCASACYC
SATSRCDPQT GACLCHAGWW GRSCNNQCAC NTSPCEQQSG RCQCRERTFG ARCERYCQCF
RGRCHPVDGT CACEPGYRGK YCREPCPAGF YGLGCRRRCG QCKGQQPCTV AEGRCLTCEP
GWNGTKCDQP CAAGFYGEGC GRRCPPCRDG HACNHVTGKC TRCNAGWIGD RCETKCSNGT
YGEDCAFVCA DCGSGHCDFQ SGRCLCSPGV HGPHCNLTCP PGLHGVDCAQ ACSCHEDSCD
PVTGACRLET NQRKGVMGAG ALLALLLGLL LSLLGCCCAC RGKDPARGEL SLGRKKAPQR
LCGRFSRISM KLPRIPLRRQ KLPKVVVAHH DLDNTLNCSF LEPPSGLEQP SPSWSSRASF
SSFDTTDEGP VYCVPHEEAA AESRDSEAPA AAPVTTPAEE AAPLPPSSDS ERSASSGDGP
GGALYARVAR REARPARVRD EARGLSLSPS PERRKPPPPD PATKPKVSWI HGKQGAGAAA
AAATAPAPSP PPAGPEAAPS PSKRKRTPSD TSARPPGLAE EGPALGAPSP PRARARGRGP
GLPEPTDAGG PPRSAPEAAS MLAAELRDKT RSLGRAEGPA GMQGPREKPA PPQKAKRSAP
PSSPARAPPA PEALGPEKAA AGAPGSDTPR KKTPIQKPPR KKSRELAGEP GRVGAPTL
//
