ID E1BIY0_BOVIN Unreviewed; 513 AA.
AC E1BIY0;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Minichromosome maintenance domain containing 2 {ECO:0000313|Ensembl:ENSBTAP00000000816.4};
GN Name=MCMDC2 {ECO:0000313|Ensembl:ENSBTAP00000000816.4,
GN ECO:0000313|VGNC:VGNC:31317};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000000816.4, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000000816.4, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000000816.4,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000000816.4}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000000816.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; E1BIY0; -.
DR STRING; 9913.ENSBTAP00000000816; -.
DR Ensembl; ENSBTAT00000000816.4; ENSBTAP00000000816.4; ENSBTAG00000000620.4.
DR VEuPathDB; HostDB:ENSBTAG00000000620; -.
DR VGNC; VGNC:31317; MCMDC2.
DR eggNOG; KOG0480; Eukaryota.
DR GeneTree; ENSGT01090000260080; -.
DR HOGENOM; CLU_032817_1_0_1; -.
DR InParanoid; E1BIY0; -.
DR OMA; AEKMIHG; -.
DR TreeFam; TF332272; -.
DR Proteomes; UP000009136; Chromosome 14.
DR Bgee; ENSBTAG00000000620; Expressed in testis and 37 other cell types or tissues.
DR ExpressionAtlas; E1BIY0; baseline.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR GO; GO:0000727; P:double-strand break repair via break-induced replication; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF75; MINICHROMOSOME MAINTENANCE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF17855; MCM_lid; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 372..454
FT /note="MCM AAA-lid"
FT /evidence="ECO:0000259|Pfam:PF17855"
SQ SEQUENCE 513 AA; 57884 MW; EAB28640BAB1D14A CRC64;
MSNLKMKEAA LIYLDRSGGL QKFIDDCKYY NDSKQSYAVY RFNVLINPSD IVELDAELGN
HILHQPLKAA QVFQSINIVL KLTHLPPLPS YYLDLCEFPR DYTSQRFYTM QGIVIAMTTV
TKYTQGARFL CSDEACPLSK GFQYIRVHVP GATESATVRN DFLCNLCSSS LQEDRKFRVL
GDKQIVEIIT AESLHAFQGY CNNQPFRFQS LTVFLRDESV NKMNIGNEYK VIGIPTCVKT
SQTAVCVEAN SITFCIPKAV ESRSITVYIS GKKFGDDVDQ QMTFPVQCSF WSFLDMDSPS
RRNIQKTNML IGQMDCSLIP ANLVEAFALL INCSESSPCH PLLPTVQHTL KKAIDPEGLL
YLASKQFTTE DFEKLLAFAK NLNVEFSLEA ERMIHGYYLA SRRIRTDSIC GSKLSASALK
YLVSLSEAHA RLNLRNKVLK EDVLIAALLF ETSLTLKYGA AVFCVAPNAV FPFEQYNEDY
LEQRDVYLTE CQQQLQQFIA TYGPGTAIFA SDE
//
