ID E1EVR6_GIAIA Unreviewed; 594 AA.
AC E1EVR6;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Kinase, NEK {ECO:0000313|EMBL:EFO65701.1};
GN ORFNames=GLP15_3140 {ECO:0000313|EMBL:EFO65701.1};
OS Giardia intestinalis (strain P15) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=658858 {ECO:0000313|EMBL:EFO65701.1, ECO:0000313|Proteomes:UP000008974};
RN [1] {ECO:0000313|EMBL:EFO65701.1, ECO:0000313|Proteomes:UP000008974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P15 {ECO:0000313|EMBL:EFO65701.1,
RC ECO:0000313|Proteomes:UP000008974};
RX PubMed=20929575; DOI=10.1186/1471-2164-11-543;
RA Jerlstrom-Hultqvist J., Franzen O., Ankarklev J., Xu F., Nohynkova E.,
RA Andersson J.O., Svard S.G., Andersson B.;
RT "Genome analysis and comparative genomics of a Giardia intestinalis
RT assemblage E isolate.";
RL BMC Genomics 11:543-543(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFO65701.1}.
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DR EMBL; ACVC01000010; EFO65701.1; -; Genomic_DNA.
DR AlphaFoldDB; E1EVR6; -.
DR STRING; 658858.E1EVR6; -.
DR EnsemblProtists; EFO65701; EFO65701; GLP15_3140.
DR VEuPathDB; GiardiaDB:GLP15_3140; -.
DR OMA; CRPYELS; -.
DR OrthoDB; 5474963at2759; -.
DR Proteomes; UP000008974; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR PANTHER; PTHR43671:SF112; NIMA-LIKE KINASE; 1.
DR PANTHER; PTHR43671; SERINE/THREONINE-PROTEIN KINASE NEK; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00248; ANK; 5.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EFO65701.1};
KW Transferase {ECO:0000313|EMBL:EFO65701.1}.
FT DOMAIN 10..263
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 594 AA; 65843 MW; 483B0F4A9CE7DE92 CRC64;
MRERLHSQFH TNSVYIRSSQ LGAVYKAERL SDGAIVAVKE ISLRNIPDDQ YVALCRPYEL
SRYLTHPHLL VYHEAYVIPG ERCLLEMELC ENGALVDVLD DLYKRKEHLE ESFVWEIIAQ
IADALVYLHD VDKPQGSVLH KAVRASSVFI GENGLKLAKL GSTRHASELT VFGTRRKHDM
YLPPEATGRR SPTDKWDIWG LGCLVVEVCT LGTVYNDSSA MLSRLSFDLR SYSDALAFMV
ASCLSMCDKD RPSAVEIKGH IEIRRALRRV NPSSVTKICN PELRAPNKHR SEDNSLQGEY
EVEAEAYDAG SDHSINTSLL NVGDGAVKTS PDEVNQSSQV DPTLSRGCMY NGLISDDLME
LILSDNSHGV SAQMDRLMSC LKTALDVAAF ESRPNVLQVI CEMIYTNALP IQISKRKGER
SLGKTPLMFA AEIGNKEKII QHLDKIMQLF YTSLPSRSDA QGVHHGANDD RYTDEVTALM
IAASANKVEA VKLLLLEIGV QNQNGMTALM FAAMNNSAEA AKYLVAEAGF KTVEGKTALM
LAVHNNAMEC VEILKGREGH IADKAGNRAI DYVRAPGTKV PLYHQERMVS ILSN
//
