ID E1F7J6_GIAIA Unreviewed; 676 AA.
AC E1F7J6;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 03-MAY-2023, entry version 42.
DE RecName: Full=DNA polymerase kappa {ECO:0000256|ARBA:ARBA00016178};
GN ORFNames=GLP15_3547 {ECO:0000313|EMBL:EFO61598.1};
OS Giardia intestinalis (strain P15) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=658858 {ECO:0000313|EMBL:EFO61598.1, ECO:0000313|Proteomes:UP000008974};
RN [1] {ECO:0000313|EMBL:EFO61598.1, ECO:0000313|Proteomes:UP000008974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P15 {ECO:0000313|EMBL:EFO61598.1,
RC ECO:0000313|Proteomes:UP000008974};
RX PubMed=20929575; DOI=10.1186/1471-2164-11-543;
RA Jerlstrom-Hultqvist J., Franzen O., Ankarklev J., Xu F., Nohynkova E.,
RA Andersson J.O., Svard S.G., Andersson B.;
RT "Genome analysis and comparative genomics of a Giardia intestinalis
RT assemblage E isolate.";
RL BMC Genomics 11:543-543(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFO61598.1}.
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DR EMBL; ACVC01000221; EFO61598.1; -; Genomic_DNA.
DR AlphaFoldDB; E1F7J6; -.
DR STRING; 658858.E1F7J6; -.
DR EnsemblProtists; EFO61598; EFO61598; GLP15_3547.
DR VEuPathDB; GiardiaDB:GLP15_3547; -.
DR OMA; MPTHVAK; -.
DR OrthoDB; 146204at2759; -.
DR Proteomes; UP000008974; Unassembled WGS sequence.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd03586; PolY_Pol_IV_kappa; 1.
DR Gene3D; 1.10.150.810; -; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR022880; DNApol_IV.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076:SF33; DNA POLYMERASE KAPPA; 1.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 4: Predicted;
FT DOMAIN 90..330
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
SQ SEQUENCE 676 AA; 75849 MW; B8B89524A7066BDD CRC64;
MNRNGLLDGT KAGLTSINRD TINKIIAQET HGTAKFLRMR EKEQASCVRS ALLAQRASAL
KPQAIREETL RVDQMIEEAT RNLRSWRNVI AVLDFDCFYA SIEERDNPRL RGKPVIITGG
SIVCTSNYAA RKYGVRSAMP THVAKALCKD VIAIPASMEK YMSVSYAAAE TFAKYDTHYS
MHGLDECIFN LTAYMERYAY EKYGVVDMWS AYAHLDEQCV DGTLSTDPDP MIPLPIVQDT
NTLFKEKPGF IELLAAEVVS ILRKDIASRL GITCSVGVAI NQQVAKIFTE LNKPDGQTIG
PLRTVTQDNY STILHSHLKD LHIRKIWGVG DASAQLLSRE PFMITSIGDI FLKRGLLSLL
LTPTQAKFYI FASVGLSSVQ QLMDQNSPKS VGQECTFPET SDEEILKNIL RNLCKLVAQK
LQEQNLVPTR LNVKVRFADW IDKTHVVNLN RHSWDLDVLY LAALEALHHI RKCKVDEVGY
PISTSSNNEG IEHGMGRGRI APYLTVGFGI YRRLARCIDI RLLGVAAHTF RECQDSNSES
VLYQLSKAGI AHRSYAKNCV KAHSVRNIDQ IRSNDVSNTE VIVISSSSSS SFSENDHYPS
ITSKTLKGDF EAEPTRQGNR VTNKLGNFNK TTVRHKVARV ERTQKLRFAA DIKEKRSFII
SSKPLHNKLR RNRSST
//
