ID E1F8V2_GIAIA Unreviewed; 854 AA.
AC E1F8V2;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Protein 21.1 {ECO:0000313|EMBL:EFO61107.1};
GN ORFNames=GLP15_2698 {ECO:0000313|EMBL:EFO61107.1};
OS Giardia intestinalis (strain P15) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=658858 {ECO:0000313|EMBL:EFO61107.1, ECO:0000313|Proteomes:UP000008974};
RN [1] {ECO:0000313|EMBL:EFO61107.1, ECO:0000313|Proteomes:UP000008974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P15 {ECO:0000313|EMBL:EFO61107.1,
RC ECO:0000313|Proteomes:UP000008974};
RX PubMed=20929575; DOI=10.1186/1471-2164-11-543;
RA Jerlstrom-Hultqvist J., Franzen O., Ankarklev J., Xu F., Nohynkova E.,
RA Andersson J.O., Svard S.G., Andersson B.;
RT "Genome analysis and comparative genomics of a Giardia intestinalis
RT assemblage E isolate.";
RL BMC Genomics 11:543-543(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFO61107.1}.
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DR EMBL; ACVC01000339; EFO61107.1; -; Genomic_DNA.
DR AlphaFoldDB; E1F8V2; -.
DR STRING; 658858.E1F8V2; -.
DR EnsemblProtists; EFO61107; EFO61107; GLP15_2698.
DR VEuPathDB; GiardiaDB:GLP15_2698; -.
DR OMA; CAVEHKQ; -.
DR OrthoDB; 2201193at2759; -.
DR Proteomes; UP000008974; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR PANTHER; PTHR24120:SF4; ANKYRIN REPEAT AND SOCS BOX PROTEIN 12; 1.
DR PANTHER; PTHR24120; GH07239P; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 5.
DR SMART; SM00248; ANK; 16.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}.
FT DOMAIN 9..282
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REPEAT 369..401
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 673..705
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 737..769
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 854 AA; 93966 MW; D49E08CD6FFEBC66 CRC64;
MTLYLPPAYD AVKYLNNDIY GINYLVRDRN LDLLATCRIV SKADVGQGRY ALIQELAKQA
HRLDHESIAP LLEAFVDDEQ ACTFLISRGV GQSLYEYNEE LCFLQVNLEE EAIMTILIEL
INAILYVYSM NRKTNFTAAL ASNLPSTGLD PLCIRLNNKG RALVDYSAFA IKLAVQRHSA
FTTAYLCPEA LRSQHSGEDR SHSNLSPLKM LAYNVGRLCC ELCFTGSRCK AVKGEYDTAY
MLKSIIEENI YSRDLVCILS WLTNPCSNLR PYLDEVLTHP FIFEFTVKLG SRENERVFRN
ALGSTQLILS ANMNNVEYVR ALVNKQKRLT NYDGATALMA AAILGNIEVL KILIPYEFGM
RMITGDSLNG ATALILAARN GQAEACKLLA PHEAKLKKRD GFTALMEATV RGHSSAADAL
MKYEAKLVIQ LDDPSNPKNG TTALMLACEF HQLHIANQLI QYEAGMRDSS GYTALHRAAA
LGLVSAVQLL ITTKECGLRD PKGQTALMFA AQYGRSKCVE LLCKEKEAGL VTDKGWSALL
SAIANEHTET AKLLIDCEGH LALNIGYTPL MCAVEHKQYE VIDLLKHNLA RKVIMTENEE
NSWHNGATAL MLAAYSNDVD SCRKLVELEE GIRNADGMTA SMIAASNDSA AALSILCMSQ
RESESKLIGG SADNRTCLMI ATLSGSLSCV RVLVERGIGV GCQDSMGSTA LIMAALSGYA
DICRVLAPIE ARVQRKDGFT ALMSAAQEGH RECVSILLSK EGDIHKPGGW TALMSAALKN
KSEIVQILSK DKRQIKQKRE KDGITALMIA VQSGHTECIR ILAPLERNLT DKKGRKCEAY
ARTEAVRRIL AKLR
//
