ID   E1IRB2_ECOLX            Unreviewed;       204 AA.
AC   E1IRB2;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Alpha-ribazole phosphatase {ECO:0000313|EMBL:EFO58132.1};
DE            EC=3.1.3.73 {ECO:0000313|EMBL:EFO58132.1};
GN   Name=cobC {ECO:0000313|EMBL:EFO58132.1};
GN   ORFNames=HMPREF9348_02709 {ECO:0000313|EMBL:EFO58132.1};
OS   Escherichia coli MS 145-7.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=679204 {ECO:0000313|EMBL:EFO58132.1, ECO:0000313|Proteomes:UP000003691};
RN   [1] {ECO:0000313|EMBL:EFO58132.1, ECO:0000313|Proteomes:UP000003691}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MS 145-7 {ECO:0000313|EMBL:EFO58132.1,
RC   ECO:0000313|Proteomes:UP000003691};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA   Chinwalla A., Mardis E.R., Wilson R.K.;
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFO58132.1}.
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DR   EMBL; ADWS01000012; EFO58132.1; -; Genomic_DNA.
DR   AlphaFoldDB; E1IRB2; -.
DR   Proteomes; UP000003691; Unassembled WGS sequence.
DR   GO; GO:0043755; F:alpha-ribazole phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR   CDD; cd07067; HP_PGM_like; 1.
DR   Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR   InterPro; IPR013078; His_Pase_superF_clade-1.
DR   InterPro; IPR029033; His_PPase_superfam.
DR   InterPro; IPR001345; PG/BPGM_mutase_AS.
DR   InterPro; IPR017578; Ribazole_CobC.
DR   NCBIfam; TIGR03162; ribazole_cobC; 1.
DR   PANTHER; PTHR48100:SF71; ADENOSYLCOBALAMIN_ALPHA-RIBAZOLE PHOSPHATASE; 1.
DR   PANTHER; PTHR48100; BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED; 1.
DR   Pfam; PF00300; His_Phos_1; 1.
DR   PIRSF; PIRSF000709; 6PFK_2-Ptase; 1.
DR   SMART; SM00855; PGAM; 1.
DR   SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR   PROSITE; PS00175; PG_MUTASE; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:EFO58132.1}.
FT   ACT_SITE        9
FT                   /note="Tele-phosphohistidine intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT   ACT_SITE        82
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT   BINDING         8..15
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
FT   BINDING         58
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
SQ   SEQUENCE   204 AA;  23456 MW;  DE4C6F1FB9C11AE9 CRC64;
     MMRLWLIRHG ETQANVDGLY SGHAPTPLTA RGIEQAQNLH TLLHGVSFDL VLCSELERAQ
     HTARLVLSDR QLPVQIIPEL NEMFFGDWEM RHHRDLMQED AENYSAWCND WQHAIPTNGE
     GFQAFSQRVE RFIARLSEFQ HYQNILVVSH QGVLSLLIAR LIGMPAEAMW HFRVDQGCWS
     TIDINQKFAT LRVLNSRAIG VENA
//