ID E1J249_ECOLX Unreviewed; 442 AA.
AC E1J249;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Pyrimidine utilization transport protein G {ECO:0000313|EMBL:EFK69973.1};
GN Name=rutG {ECO:0000313|EMBL:EFK69973.1};
GN ORFNames=HMPREF9347_00950 {ECO:0000313|EMBL:EFK69973.1};
OS Escherichia coli MS 124-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=679205 {ECO:0000313|EMBL:EFK69973.1, ECO:0000313|Proteomes:UP000003390};
RN [1] {ECO:0000313|EMBL:EFK69973.1, ECO:0000313|Proteomes:UP000003390}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS 124-1 {ECO:0000313|EMBL:EFK69973.1,
RC ECO:0000313|Proteomes:UP000003390};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFK69973.1}.
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DR EMBL; ADWT01000005; EFK69973.1; -; Genomic_DNA.
DR RefSeq; WP_001347171.1; NZ_ADWT01000005.1.
DR AlphaFoldDB; E1J249; -.
DR Proteomes; UP000003390; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR GO; GO:0015218; F:pyrimidine nucleotide transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR019918; Pyrimidine_permease_RutG_pred.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; TIGR03616; RutG; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 60..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 442 AA; 45601 MW; 0F2634B37ABB08A5 CRC64;
MAMFGFPHWQ LKSTSTESGV VAPDERLPFA QTAIMGVQHA VAMFGATVLM PILMGLDPNL
SILMSGVGTL LFFFITGGRV PSYLGSSAAF VGVVIAATGF NGQGINPNIS IALGGIIACG
LVYTVIGLVV MKIGTRWIER LMPPVVTGAV VMAIGLNLAP IAVKSVSASA FDSWMAVMTV
LCIGLVAVFT RGMIQRLLIL VGLIVACLLY GVMTNLLGLG KAVDFTLVSH AAWFGLPHFS
TPAFNSQAMM LIAPVAVILV AENLGHLKAV AGMTGRNMDP YMGRAFVGDG LATMLSGSVG
GSGVTTYAEN IGVMAVTKVY STLVFVAAAV IAMLLGFSPK FGALIHTIPA AVIGGASIVV
FGLIAVAGAR IWVQNRVDLS QNGNLIMVAV TLVLGAGDFA LTLGGFTLGG IGTATFGAIL
LNALLSRKLV DVPPPEVVHQ EP
//
