ID E1L606_9FIRM Unreviewed; 475 AA.
AC E1L606;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612};
DE EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612};
GN Name=pgi {ECO:0000313|EMBL:EFL56261.1};
GN ORFNames=HMPREF9321_0466 {ECO:0000313|EMBL:EFL56261.1};
OS Veillonella atypica ACS-049-V-Sch6.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Veillonella.
OX NCBI_TaxID=866776 {ECO:0000313|EMBL:EFL56261.1, ECO:0000313|Proteomes:UP000004211};
RN [1] {ECO:0000313|EMBL:EFL56261.1, ECO:0000313|Proteomes:UP000004211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS-049-V-Sch6 {ECO:0000313|EMBL:EFL56261.1,
RC ECO:0000313|Proteomes:UP000004211};
RA Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate;
CC Xref=Rhea:RHEA:11816, ChEBI:CHEBI:57634, ChEBI:CHEBI:58225;
CC EC=5.3.1.9; Evidence={ECO:0000256|RuleBase:RU000612};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 2/4.
CC {ECO:0000256|RuleBase:RU000612}.
CC -!- SIMILARITY: Belongs to the GPI family. {ECO:0000256|RuleBase:RU000612}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFL56261.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEDR01000026; EFL56261.1; -; Genomic_DNA.
DR RefSeq; WP_005376868.1; NZ_AEDR01000026.1.
DR AlphaFoldDB; E1L606; -.
DR eggNOG; COG0166; Bacteria.
DR UniPathway; UPA00109; UER00181.
DR Proteomes; UP000004211; Unassembled WGS sequence.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR CDD; cd05016; SIS_PGI_2; 1.
DR InterPro; IPR001672; G6P_Isomerase.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR035482; SIS_PGI_2.
DR PANTHER; PTHR11469; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR11469:SF1; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF00342; PGI; 1.
DR PRINTS; PR00662; G6PISOMERASE.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51463; P_GLUCOSE_ISOMERASE_3; 1.
PE 3: Inferred from homology;
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432,
KW ECO:0000256|RuleBase:RU000612};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152, ECO:0000256|RuleBase:RU000612};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU000612}.
SQ SEQUENCE 475 AA; 53528 MW; 849A94AC68226786 CRC64;
MLQLDSGFEL DYNNIYNESC IQARDIQNFE RAIQNVWRHT NILRSTGYEE GHLSKDGQPE
PILFYQLPYI SESGINTPDM MDRLHDLGEY ARQHIDTVVS IGIGGSYLGS KVLFDVQCGS
FWNNYTDEER NGYPRFYFAG FNVDGPYLEG LIKTLLSQAD EKGSDYKVML VVTSKSGSTI
EPMANFMILQ KALEDNHINY EVTVVTDTND AAHPTILHDM AIKHQWRTFS VPYGVGGRFS
VFTEVGFVTA ALVGFDIEGF LAGAASMDMA CQEEDVYKNP ALFSALLKYI ASERYGRIIE
VFMPYGESLH SLSDWYVQLL SESLGKMSNT CLPYGRTPVP AVGTMDMHAQ VQEHQEGRLN
KVVQFIKVRD WNTSLVVPNL YSEYDKLDAI GDIPISDILN SALDANREAL SIDNRFNMTI
SVPTLNAFHL GEIMFMHCWA VYFESILAGV DAFDQPGVEV YKRLIGPKLQ AMKKL
//
