ID E1SVG0_FERBD Unreviewed; 499 AA.
AC E1SVG0;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Tryptophan halogenase {ECO:0000313|EMBL:ADN75306.1};
GN OrderedLocusNames=Fbal_1097 {ECO:0000313|EMBL:ADN75306.1};
OS Ferrimonas balearica (strain DSM 9799 / CCM 4581 / KCTC 23876 / PAT).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Ferrimonadaceae; Ferrimonas.
OX NCBI_TaxID=550540 {ECO:0000313|EMBL:ADN75306.1, ECO:0000313|Proteomes:UP000006683};
RN [1] {ECO:0000313|EMBL:ADN75306.1, ECO:0000313|Proteomes:UP000006683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9799 / CCM 4581 / KCTC 23876 / PAT
RC {ECO:0000313|Proteomes:UP000006683};
RX DOI=10.4056/sigs.1161239;
RA Nolan M., Sikorski J., Davenport K., Lucas S., Glavina Del Rio T., Tice H.,
RA Cheng J., Goodwin L., Pitluck S., Liolios K., Ivanova N., Mavromatis K.,
RA Ovchinnikova G., Pati A., Chen A., Palaniappan K., Land M., Hauser L.,
RA Chang Y., Jeffries C., Tapia R., Brettin T., Detter J., Han C.,
RA Yasawong M., Rohde M., Tindall B., Goker M., Woyke T., Bristow J.,
RA Eisen J., Markowitz V., Hugenholtz P., Kyrpides N., Klenk H., Lapidus A.;
RT "Complete genome sequence of Ferrimonas balearica type strain (PAT).";
RL Stand. Genomic Sci. 3:174-182(2010).
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DR EMBL; CP002209; ADN75306.1; -; Genomic_DNA.
DR RefSeq; WP_013344612.1; NC_014541.1.
DR AlphaFoldDB; E1SVG0; -.
DR STRING; 550540.Fbal_1097; -.
DR GeneID; 67181335; -.
DR KEGG; fbl:Fbal_1097; -.
DR eggNOG; COG0665; Bacteria.
DR HOGENOM; CLU_022247_1_0_6; -.
DR OrthoDB; 7178350at2; -.
DR Proteomes; UP000006683; Chromosome.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006905; Flavin_halogenase.
DR InterPro; IPR033856; Trp_halogen.
DR PANTHER; PTHR43747; FAD-BINDING PROTEIN; 1.
DR PANTHER; PTHR43747:SF4; FLAVIN-DEPENDENT TRYPTOPHAN HALOGENASE; 1.
DR Pfam; PF04820; Trp_halogenase; 1.
DR PIRSF; PIRSF011396; Trp_halogenase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR011396-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR011396-2};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR011396-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000006683}.
FT ACT_SITE 76
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-1"
FT BINDING 11..14
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 76
FT /ligand="7-chloro-L-tryptophan"
FT /ligand_id="ChEBI:CHEBI:58713"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 182
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 329
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 338
FT /ligand="L-tryptophan"
FT /ligand_id="ChEBI:CHEBI:57912"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 342
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
SQ SEQUENCE 499 AA; 56013 MW; 550E746B653379C9 CRC64;
MQRQQVVILG GGSAGWMTAA MLARVLGSAV SLTLVESEQI GTVGVGEASI PPLALFNQAL
GIDEAEFMAA TAATFKLGIQ FEHWGQQGDR YLHAFGAIGR DLGLTPFHHL WLQQQPDEVA
DLWQYSLNAQ AAEQHRFARL DRIDGTPLAG LTHAYHFDAG RYAAYLRQYA EQRGVVRIEG
RVEQVEQAAN GDIQALRLAD GRRIEGQLFI DCSGLAARLI EQTLGSGFED WSHWLPCDRA
WAVPSANTDT LRPYTRAIAR EAGWQWQIPL QHRTGNGLVF ASRFLDEENA RQQLLANLDS
EPLAEPRLIR FRVGRRRQQW HRNCIAIGLS SGFLEPLEST SIHLIQSAIM RLVKLFPSAQ
GEMDALRDSF NRESQREFEQ VRDFIILHYH LNQRGDAPLW RHTRTMALPE SLAAKLALFG
ESGRLLRQQD ELFTEVAWMQ VMLGQGLVPK SVHPLAQSLS PAQLQEFLLN LRTIIGHTAG
RLPSHQDFLA RYCPMPNTP
//
