ID E1TDS1_BURSG Unreviewed; 485 AA.
AC E1TDS1;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase {ECO:0000313|EMBL:ADN60023.1};
GN OrderedLocusNames=BC1003_4087 {ECO:0000313|EMBL:ADN60023.1};
OS Burkholderia sp. (strain CCGE1003).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=640512 {ECO:0000313|EMBL:ADN60023.1};
RN [1] {ECO:0000313|EMBL:ADN60023.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCGE1003 {ECO:0000313|EMBL:ADN60023.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Daligault H., Davenport K., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N., Ovchinnikova G.,
RA Martinez-Romero E., Rogel M.A., Auchtung J., Tiedje J.M., Woyke T.;
RT "Complete sequence of chromosome2 of Burkholderia sp. CCGE1003.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP002218; ADN60023.1; -; Genomic_DNA.
DR AlphaFoldDB; E1TDS1; -.
DR STRING; 640512.BC1003_4087; -.
DR KEGG; bgf:BC1003_4087; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_0_0_4; -.
DR OrthoDB; 6187633at2; -.
DR GO; GO:0018480; F:5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity; IEA:InterPro.
DR GO; GO:1901023; P:4-hydroxyphenylacetate catabolic process; IEA:InterPro.
DR CDD; cd07093; ALDH_F8_HMSADH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR011985; DH_HpaE.
DR NCBIfam; TIGR02299; HpaE; 1.
DR PANTHER; PTHR43720; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43720:SF2; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 15..471
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 242
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 485 AA; 52271 MW; E3D17D452F39DDF7 CRC64;
MRIDHLINGK TAGAKDYFET VNPATQQVLA EVARGGAEEI HAAVRAAKEA FPAWAAKSAS
ERAKLVRKLG ELIAKSVPDI SETETKDTGQ TISQTRKQLV PRAADNFSYF AEMCTRVDGH
TYPTDTHLNY TLFQPVGVCA LISPWNVPFM TATWKVAPCL AFGNTAVLKM SELSPLTASM
LGALALEAGI PAGVLNVVHG FGKETGEPLV AHPDVRAVSF TGSTATGNRI VQTAGLKKFS
MELGGKSPFV VFDNADLERA LDAALFMIFS NNGERCTAGS RILVQKSIYA EFAQRFVERA
KRLTVGDPLA ESTIIGPMIS QGHLAKVRSY IELGPKEGAT LACGGLDAPD LPDALRKGNF
VMPTVFVDVD NRMRIAQEEI FGPVACLIPF DDEAHAIRLA NDISYGLSSY IWTENTGRAH
RVAAAVEAGM CFVNSQNVRD LRQPFGGTKA SGVGREGGTW SYEVFLEPKN VCVSLGSHHI
PRWGV
//
