ID E2AF25_CAMFO Unreviewed; 1981 AA.
AC E2AF25;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Anaphase-promoting complex subunit 1 {ECO:0000313|EMBL:EFN67980.1};
GN ORFNames=EAG_10518 {ECO:0000313|EMBL:EFN67980.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN [1] {ECO:0000313|EMBL:EFN67980.1, ECO:0000313|Proteomes:UP000000311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SIMILARITY: Belongs to the APC1 family.
CC {ECO:0000256|ARBA:ARBA00010547}.
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DR EMBL; GL438984; EFN67980.1; -; Genomic_DNA.
DR STRING; 104421.E2AF25; -.
DR EnsemblMetazoa; XM_011258668.3; XP_011256970.2; LOC105251697.
DR InParanoid; E2AF25; -.
DR OMA; MQPPDSR; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR024990; Apc1.
DR InterPro; IPR048971; Apc1_3rd.
DR InterPro; IPR041221; APC1_C.
DR InterPro; IPR046794; Apc1_MidN.
DR InterPro; IPR049255; Apc1_N.
DR InterPro; IPR011989; ARM-like.
DR PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR Pfam; PF12859; ANAPC1; 1.
DR Pfam; PF21282; APC1_3rd; 1.
DR Pfam; PF18122; APC1_C; 1.
DR Pfam; PF20518; Apc1_MidN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000311};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 66..176
FT /note="Anaphase-promoting complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12859"
FT DOMAIN 695..1020
FT /note="Anaphase-promoting complex subunit 1 middle"
FT /evidence="ECO:0000259|Pfam:PF20518"
FT DOMAIN 1650..1735
FT /note="Anaphase-promoting complex subunit 1 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF21282"
FT DOMAIN 1769..1942
FT /note="Anaphase-promoting complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18122"
FT REGION 337..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1981 AA; 222322 MW; E6CFFC4A66901117 CRC64;
MIAASEPVEY TPGGRQIILK HPGSLISQQL SNNRTTCGEN ILLKKFSEVN ISEKSPKETW
LVRSNKTCGE EELYYSGKVA VHCKGNQNTR VLEATYTCET DIKHALWCTF HTSIPDHLTK
GKEYKAEDSI HKSLECICLL DSYTLKVFTE CGEDYVSTLQ FQVSAVWPTK YGIILEKCQV
PIIDSRYISF ENSRLPNQND NLPVAFSLMH PLDEICPLLI KHGSLSYMNE SSQQIIFTSS
EPSFAVIYDT KSGLHSVYKI RKALAEECQI VCGINDTSLL NHSVNMSSLN VGSNLSINKS
CTNKGHQSPF LLGIPNLQMS NNTGIGLGLS NTPFGSRTGS YSTASGGPSP QQQQHSRSQS
SMATISRCQS PTHSAALSPL LGVPTNSNIY NRLHQTVMIT TSSQIHSPIT SYNNVQLKGA
AIASKPLYPE VCLEHVWTEN VGISKDIVYG RASKVFLTSD LVGQTYLGYL VPNRLQLFLV
RLEKTNKQQQ IIFGMITNIA AKDAVNLSNL HMIAIVDLSN GIALYTGVTC VGKLHMSGIL
SNLTGSNYFL SNSNSKIASP FPRRSSLICQ NCAPSHEVKF EESMHLLSPV GGNCARPPIL
LENSLLDTNF LALKDAVGNE ITVECGKKQY FRITLPVSST SPLVTKCLHT LRSVLQRDLA
MQLLVKWYGA RNAPGPQDFS PAQEWDLFLV VLFTLLGYDV EKLHLIRNNE KDQFTEYNSN
SPTVLPKKQK TNNCGSVDDW LYILESNEFK NSQFFISNIL NSQKISSFLC TIPKNAAESN
NIGKINVQAA LYPHLPLVLF SLHLLYEELK LNSVILESLP LLGQLLYQLS IDLKFEMYAH
HYFLDSPSLS YLKSVKSQIS DSDLQKITIP NYIPRKPPNI FETLNSMLNG IETNAFPYLS
HVNRRTRNVI YLTVLVANEN RVDVIEMEKY IKLIIPAGSR IDLQENGGKS DKEIWKKMEK
PATDRIILMY HEMGMTKEDL EILPPAISLM IKDVMHRCRE CPPSNWPMHA YELVDRQDLA
ALDKHLKSSS RLQYIDGETK DYGIKDEHDD GMEFDDMILK LRFSKDHRVA EVRRLLNSSK
PVKIAIVQRS NVSDHEFIEE QERHLHTLCT RTMALPVARG MFTLRTSTPM ITEQLPIPRL
CLTGKAPPRG NTVELTHIDV APNMNLWPLF HNGVAAGLCI HPDAANIDST WIVYNKQQQG
EYGVEHSGFL MALGLNGHLK NLAPLSTYEY LADCHEATSV GLLLGLSATH RGTMNVSMTK
LLSLHVETLL PPTSIELNVQ QNVQIAALMG VGLVYQGTAH RHISHALLSE IGRPPGPEMK
NCVDRESYSL TAGLALGLVI LGSGGGADVP ASIPDTLHYY MVGGYTRPFS GAQKDKYKSP
SYQIREGDSI NIDVTSPGAT IALGLMYFNT GNRAVAEWMQ PPDTQYLLEF VRPDFLLLRV
LAKSLILWDD IEPTKSWVSS HVPNIVYKYR LQKPTPEITQ NVDLETINQA YCNIIAGACM
ALGLRYAGTA NKNAFKTLYN YAQMFTALSH KTIAELAGKS TVETCLNVVL LSTAVIMAGT
GDLDIIRICR HIRTRIGPAS GVVTYGSHLA THMALGLLFL GGGRYTLSNS PNAVAALIIS
LFPKFPTHSN DNRYHLQALR HLYVLAAEPR IILPRDIDTG QYCYATIHLT FETDREAEGQ
EISLQAPCLL PQLCNLKKIE LKDTRYWTII FEKHHNWQQL ENMLERHDFL SIKQRAGCLS
YLEDPRGFRS LVAQTLTTEN AVAWAARPEY VTSFTNDKTV LNIITYFLQW SKKEINPSEN
IKYSLQNGSQ WEMPEFERYF LHVFAIIVYE CITKDKVNLI PLWLRIIKNL KVIEEKPNSF
SIWQIKLLSS QLSKRINSID DANLLLSLES MLAIKQKTAV ILDKWEHDMK PLFKQYLTNG
MVQADTVSLA RMCAYFIFYG IPYPIDDKII YSFECRWNYM ASPLFGHGKT TDWFMSVLDP
Y
//
