ID E2BFT5_HARSA Unreviewed; 685 AA.
AC E2BFT5;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Rhodopsin, GQ-coupled {ECO:0000313|EMBL:EFN85473.1};
GN ORFNames=EAI_14818 {ECO:0000313|EMBL:EFN85473.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN85473.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN85473.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|ARBA:ARBA00010663}.
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DR EMBL; GL448039; EFN85473.1; -; Genomic_DNA.
DR AlphaFoldDB; E2BFT5; -.
DR STRING; 610380.E2BFT5; -.
DR EnsemblMetazoa; XM_011139678.3; XP_011137980.1; LOC105182332.
DR InParanoid; E2BFT5; -.
DR OMA; SLMGPHY; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd00637; 7tm_classA_rhodopsin-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24249:SF421; G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24249; HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 54..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..315
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 342..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 499..542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..522
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..591
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 596..610
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 611..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 627..676
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 74203 MW; 6EF23014D5F74683 CRC64;
MKSLNCKIPS DIKKRRRTKH PDSASVKTTN EVDANHLLCL LCSQTQQQQT ANTLLLIHLG
AVEAAVCLIL LIFTTGPWPV AGTWCVLHGF LLALLHPVAL WTVTGLNCDR YYAIAAPLHY
AALVSPRRVA VGLVASWTGA LLLCLPPFSG LVPPYRYSPG LGCCAPDFGN DTWGSAAALY
GAVYAILGLG LPAVLVTVCN LRVLGIARYH RHRIASAIYE VTLSAQVTIT HQRNPFFVPT
VTAPSAGGPP RFHSAASTVM QLVGSLYLLY FPYCGLILWE ACSAANQHRL HAHPRLASLA
SFLLACSPPI NCLLYGLKSQ TLRRSVQNYW RKKATKSELQ QEIQARTPSV AGSRRPSGSG
NASFFPFPPL QRRLSEALLA LGSCRSGGTF GSNNLGFHRG RLQPAASCNT LRVPATESGE
PSKLVRASAS AASLMGPHYR SDFIGADLDA GCSIAMCETP RRSPRILITR AYSEESQDGG
SPLLRKPFAC NTNPPPCEKR RWRHCSTGSE SSTGSSDASV WTTGVPPKYV KSNAKSTDGW
SSSRRYIRGK NLEEGALSSV IRPSNNSESS DTTDTTTATT TTTTLLKSLA IENNGQGDRG
KEKVNGNMQK REYSESESSW SSVEEIETKA ITERNDEDFA RTTDEPRTRP PRRKSKGGSA
GNHEPEVAED REKAAQLRPL LTPSS
//
