ID E2BKE6_HARSA Unreviewed; 1226 AA.
AC E2BKE6;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=EAI_02644 {ECO:0000313|EMBL:EFN83831.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN83831.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN83831.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
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DR EMBL; GL448784; EFN83831.1; -; Genomic_DNA.
DR RefSeq; XP_011140515.1; XM_011142213.2.
DR RefSeq; XP_011140516.1; XM_011142214.2.
DR AlphaFoldDB; E2BKE6; -.
DR STRING; 610380.E2BKE6; -.
DR EnsemblMetazoa; XM_011142213.2; XP_011140515.1; LOC105183831.
DR GeneID; 105183831; -.
DR KEGG; hst:105183831; -.
DR InParanoid; E2BKE6; -.
DR OMA; FLCVFPQ; -.
DR OrthoDB; 5405019at2759; -.
DR PhylomeDB; E2BKE6; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17943; DEADc_DDX20; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47958; ATP-DEPENDENT RNA HELICASE DBP3; 1.
DR PANTHER; PTHR47958:SF89; ATP-DEPENDENT RNA HELICASE DDX20-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EFN83831.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237}.
FT DOMAIN 24..52
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 55..225
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 260..405
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 882..909
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 929..955
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 24..52
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
FT COMPBIAS 932..954
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1226 AA; 140307 MW; 202F17FCF3D4BCEB CRC64;
MFRYTAHDIN KKLRTSDIKI QENVTFLEMG LPEKIMDGLS FAGFERPSPI QLKAIPIGRC
GFDLILRAKS GTGKTAVFGI IALEILDIQI SSPQVLIVAP TREIAIQISN VLKTIGSEIK
GLKVEYFVGG LSVEDDKKRL NECHVAVGAP GRIKHLIDKK LLKVSTVRLF VLDEADKLME
TNFQKDINYI FSKLSLNKQV IASSATYPGD LEKFLEMYMC SPVLISPDLD GPILVGIKQF
LVVVSSHLNA MKQVQIKVDE LQKIFTKIPF KQSLVFSNYQ SRAQSVSNKL NSMGFSSTYI
IGSQDMAKRL EIMEKLRNFN CRILMTTDLT ARGIDVENVN LVINLDIPMD AATYLHRIGR
AGRYGTHGIS ITIVSENELQ SFRELLISVG GPNFYLFKLG PDYVEDVWAD NITVFEKVYS
KPEANGTELS DIDKGILESE NGTPMAILTS ENTTFSTSSY NSKHIDTNTC SLENSGTNNT
ANLSNGNQNK SKSILSKDKK CDKAITNETY TKRKKFYLDD KRKLFYNKHN ISKVDVQQSD
EFEKREEASV IEPILPDLSS SEKMFRFTVK SHTDELSVLE KLNENVVLET NLLSIEDREL
SDDEIKQICG CISIPTADKK EESDILSAVM TDNNVISMSQ EIAQDKCSLK NSDLEHCAKL
NTEELDARSR ERNKLYDYLS KCIEEFNETD ETPLAAATRW KDKLHFEIEL LNNMFKNMTD
SIHKLVYEEH YSAFIHFFSM QKRAFLCIFP ELRTEEEVND TYVYSGLNSN NNLLDMYREI
EEFKSRFEES RSKFNAHFPY PTNADEHLPN LMMSDSEIEE YRKALRYFKE YKDPNEKLSE
ILDYIVFLSE TEKCDLMQKI KDQNLSFSDM KEFLKEETMK NDSKRVELSE DDVQQFENSD
DDTEQHETTA EVDASRIKIE YENCSRKVQN TRPGEVVDDD QGRHEPDDMK NDTSTDIIIG
HLNDSKMLSP TEMRENGASS SVSFNNDEVS NTDKDVFNCS QRAKFMSNVR RKTSQSDTKS
NVSTKYTPVQ TNNVLYNNMS ELHGKLDKHV MSNMDTNKSA DVNLYSKMPA SHAAENTKTA
FPGRSLDSTA RLSHPRVSDY ATLNSCADNR DFNIDRKFSD CEYAKEEETS LLDQIGRFSS
HTEYATNHYF PHMHDKTSWY SVRKDTSNHH EESPKTRGLD DLAYNNVYLQ NMDVDRFLSS
LRMQTNQLHL QIYQSQMLEN WISYEE
//
