ID E2M0B6_MONPE Unreviewed; 459 AA.
AC E2M0B6;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN ORFNames=MPER_13090 {ECO:0000313|EMBL:EEB88886.1};
OS Moniliophthora perniciosa (strain FA553 / isolate CP02) (Witches'-broom
OS disease fungus) (Marasmius perniciosus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Marasmiaceae; Moniliophthora.
OX NCBI_TaxID=554373 {ECO:0000313|EMBL:EEB88886.1, ECO:0000313|Proteomes:UP000000741};
RN [1] {ECO:0000313|EMBL:EEB88886.1, ECO:0000313|Proteomes:UP000000741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FA553 / isolate CP02 {ECO:0000313|Proteomes:UP000000741};
RX PubMed=19019209; DOI=10.1186/1471-2164-9-548;
RA Mondego J.M., Carazzolle M.F., Costa G.G., Formighieri E.F., Parizzi L.P.,
RA Rincones J., Cotomacci C., Carraro D.M., Cunha A.F., Carrer H., Vidal R.O.,
RA Estrela R.C., Garcia O., Thomazella D.P., de Oliveira B.V., Pires A.B.,
RA Rio M.C., Araujo M.R., de Moraes M.H., Castro L.A., Gramacho K.P.,
RA Goncalves M.S., Neto J.P., Neto A.G., Barbosa L.V., Guiltinan M.J.,
RA Bailey B.A., Meinhardt L.W., Cascardo J.C., Pereira G.A.;
RT "A genome survey of Moniliophthora perniciosa gives new insights into
RT Witches' broom disease of cacao.";
RL BMC Genomics 9:548-548(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.49;
CC Evidence={ECO:0000256|ARBA:ARBA00024557};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEB88886.1}.
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DR EMBL; ABRE01017892; EEB88886.1; -; Genomic_DNA.
DR AlphaFoldDB; E2M0B6; -.
DR STRING; 554373.E2M0B6; -.
DR KEGG; mpr:MPER_13090; -.
DR HOGENOM; CLU_595948_0_0_1; -.
DR InParanoid; E2M0B6; -.
DR OMA; LRWENIM; -.
DR OrthoDB; 1588007at2759; -.
DR Proteomes; UP000000741; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR42648; TRANSPOSASE, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR42648:SF11; TRANSPOSON TY4-P GAG-POL POLYPROTEIN; 1.
DR Pfam; PF00665; rve; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000741};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464};
KW Transposition {ECO:0000256|ARBA:ARBA00022578}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..459
FT /note="Integrase catalytic domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003161154"
FT DOMAIN 125..292
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 393..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..432
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 459 AA; 52409 MW; 1DA5DA8115D1ACFC CRC64;
MRKPSPRAFG VHLLHRLLFV KCEFLLPPQV DIESTLPETS LAAFPIPSED FLLAAPAFPI
RAKDRTLAHD ILGHPGDYIL DQVLSGKCGK GFETYLKARI SQPCKCDACI EGKAPQLPYA
TPANRASRPL ELIHMDTCGP FPVASPHGNL YFHFFLDDYT NANAVVFLRD RSQVPRAVKT
VLLRWENIME AKIVTVRCDG SAEQAEGELM EWYHDRGITV QVTAPYAHGQ NGKSEKGIRT
LEDDMHVLLS WSNLPLSFWE DAVRTASYTR FRLPTTTLPK FMTPYEMVHK QQPDYRYWHP
FGCRCWVAIP SELLLKGSAR RFEAIFVGYE EGRIGWRVRD LHGCYRFSRD VVFDDNVPGY
LGRVPDDYYA PVESGTPKLP PAENVTREVL PTDLLSPPIS PETDTVFPRA RPTHETDSSE
LRARPRKTRE LTEKGRVWQE GIKARDLHRE ELRRRRAAR
//
