ID E2ZHV0_9FIRM Unreviewed; 369 AA.
AC E2ZHV0;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Anaerobic sulfatase maturase {ECO:0000313|EMBL:EFQ07237.1};
DE EC=1.1.99.- {ECO:0000313|EMBL:EFQ07237.1};
GN ORFNames=HMPREF9436_01239 {ECO:0000313|EMBL:EFQ07237.1};
OS Faecalibacterium cf. prausnitzii KLE1255.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Faecalibacterium.
OX NCBI_TaxID=748224 {ECO:0000313|EMBL:EFQ07237.1, ECO:0000313|Proteomes:UP000006028};
RN [1] {ECO:0000313|EMBL:EFQ07237.1, ECO:0000313|Proteomes:UP000006028}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KLE1255 {ECO:0000313|EMBL:EFQ07237.1,
RC ECO:0000313|Proteomes:UP000006028};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the radical SAM superfamily. Anaerobic
CC sulfatase-maturating enzyme family. {ECO:0000256|ARBA:ARBA00023601}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFQ07237.1}.
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DR EMBL; AECU01000105; EFQ07237.1; -; Genomic_DNA.
DR RefSeq; WP_005941139.1; NZ_GL538309.1.
DR AlphaFoldDB; E2ZHV0; -.
DR STRING; 748224.HMPREF9436_01239; -.
DR eggNOG; COG0641; Bacteria.
DR HOGENOM; CLU_009273_10_0_9; -.
DR OrthoDB; 9808591at2; -.
DR BioCyc; FCF748224-HMP:GTSS-2462-MONOMER; -.
DR Proteomes; UP000006028; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21120; SPASM_anSME; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR034485; Anaerobic_Cys-type_sulfatase-m.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR047207; SPASM_anSME.
DR InterPro; IPR023867; Sulphatase_maturase_rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR NCBIfam; TIGR03942; sulfatase_rSAM; 1.
DR PANTHER; PTHR43273; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR PANTHER; PTHR43273:SF3; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDF00289; anaerobic_Cys-type_sulfatase-m; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SFLD; SFLDG01384; thioether_bond_formation_requi; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:EFQ07237.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 1..238
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 369 AA; 41404 MW; E5AE232E58ABD623 CRC64;
MKHNTFLVKP ASSLCNLRCR YCFYDDVSNS RACKNMGLLS HEMAGELVEK AFAATEEGGS
VHFLFQGGEP TLAGLDFFRF FLETERSMQR NISVFHSIQT NGICLDEEWA SFFKANSFLV
GLSLDGTQEN HDLYRLDAAG QGTWDKVTHA LALLDAYRVE TNLLCVVTGQ LARKPQRAFK
SLCELGQHNL QFIPCLDPLD TIGGQAYSLT PELYGRFLCG VFDTWYQQLQ RGNYISVRNF
EDYLRILLGM PPTSCASSGS CGHYLTVEGD GSLYPCDFYV LDEWKLGNLS HCTVEDALDS
PTSQTFLAQG RKRPAECAAC AYQLLCRGGC KRDWDASGSN RFCAAYKQFF AYVLPRLHTA
THFLAQQNR
//
