ID   E3C7U8_9LACO            Unreviewed;       393 AA.
AC   E3C7U8;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=ROK family protein {ECO:0000313|EMBL:EFQ53200.1};
GN   ORFNames=HMPREF9265_0280 {ECO:0000313|EMBL:EFQ53200.1};
OS   Limosilactobacillus oris PB013-T2-3.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Limosilactobacillus.
OX   NCBI_TaxID=908339 {ECO:0000313|EMBL:EFQ53200.1, ECO:0000313|Proteomes:UP000003070};
RN   [1] {ECO:0000313|EMBL:EFQ53200.1, ECO:0000313|Proteomes:UP000003070}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB013-T2-3 {ECO:0000313|EMBL:EFQ53200.1,
RC   ECO:0000313|Proteomes:UP000003070};
RA   Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA   Nelson K.E.;
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcriptional repressor of xylose-utilizing enzymes.
CC       {ECO:0000256|ARBA:ARBA00002486}.
CC   -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC       {ECO:0000256|ARBA:ARBA00006479}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFQ53200.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AEKL01000047; EFQ53200.1; -; Genomic_DNA.
DR   RefSeq; WP_003712758.1; NZ_AEKL01000047.1.
DR   AlphaFoldDB; E3C7U8; -.
DR   eggNOG; COG1940; Bacteria.
DR   OrthoDB; 9796533at2; -.
DR   Proteomes; UP000003070; Unassembled WGS sequence.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000600; ROK.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR18964:SF177; N-ACETYLMANNOSAMINE KINASE; 1.
DR   PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR   Pfam; PF13412; HTH_24; 1.
DR   Pfam; PF00480; ROK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01125; ROK; 1.
PE   3: Inferred from homology;
SQ   SEQUENCE   393 AA;  44328 MW;  ED52BD70E6A9AFE8 CRC64;
     MTIDHRNLSR INNRKLVLQQ LFNNQETSRA EIARQLKLNK STVSSIYTEL DDAGLIQEVR
     QGESTSSGGR KPNLVRLNPN YGFVASFNIG TAYMASMFNY INGEIIRYNR QPIERFDILT
     IMQMIKKEIQ QMQEFDQTNR GLLAIAFSIH GIVYNNKVLD SPFLDLDGID LQGYFEKEFG
     VPVVLENEAN LSAVFENDFC VADNIRDLIT ISIHRGIGVG VIANGQLYRG NRGMAGEIGR
     TLMIDRFATG SKKLVKMESL CSEDAIIGQV KAVKGIDKIS SAELVRLYHY DSQVLQIFDH
     AAELIAEASY NAIVSFGPQE VYFNSTLFED IPELYEQIRT KLVEMGAFSP IKKIVGSRMT
     SLLGASSLAI HRALQLDHYQ LRLRWPNEVK NVE
//