ID E3CTS8_DROME Unreviewed; 556 AA.
AC E3CTS8;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=RT10225p {ECO:0000313|EMBL:ADP30895.1};
DE SubName: Full=RT11149p {ECO:0000313|EMBL:ADY17759.1};
DE Flags: Fragment;
GN Name=Eph-RC {ECO:0000313|EMBL:ADP30895.1};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227 {ECO:0000313|EMBL:ADP30895.1};
RN [1] {ECO:0000313|EMBL:ADP30895.1}
RP NUCLEOTIDE SEQUENCE.
RA Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S.;
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; BT125744; ADP30895.1; -; mRNA.
DR EMBL; BT126060; ADY17759.1; -; mRNA.
DR AlphaFoldDB; E3CTS8; -.
DR HOGENOM; CLU_000288_141_4_1; -.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0005003; F:ephrin receptor activity; IEA:InterPro.
DR CDD; cd10319; EphR_LBD; 1.
DR CDD; cd00063; FN3; 2.
DR Gene3D; 2.60.40.1770; ephrin a2 ectodomain; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 1.
DR InterPro; IPR001090; Ephrin_rcpt_lig-bd_dom.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001426; Tyr_kinase_rcpt_V_CS.
DR PANTHER; PTHR46877; EPH RECEPTOR A5; 1.
DR PANTHER; PTHR46877:SF14; RECEPTOR PROTEIN-TYROSINE KINASE; 1.
DR Pfam; PF01404; Ephrin_lbd; 1.
DR Pfam; PF00041; fn3; 2.
DR SMART; SM00615; EPH_lbd; 1.
DR SMART; SM01411; Ephrin_rec_like; 1.
DR SMART; SM00060; FN3; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS51550; EPH_LBD; 1.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS00790; RECEPTOR_TYR_KIN_V_1; 1.
PE 2: Evidence at transcript level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 1..184
FT /note="Eph LBD"
FT /evidence="ECO:0000259|PROSITE:PS51550"
FT DOMAIN 307..415
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 451..544
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADP30895.1"
FT NON_TER 556
FT /evidence="ECO:0000313|EMBL:ADP30895.1"
SQ SEQUENCE 556 AA; 62386 MW; 8410C18727CD1884 CRC64;
DQVVLLDTTR EATLEWTRYP YGPQAQTPGW VEESFTDFVK GINWRSYVVC DVAYHNVNNW
LWSPFIDRGS ANRLYIEIQF TIRDCSLFPG NALSCKETFS LLFYEFDAAT REPPPWQTDS
YRLIARIAAG EGRFNQNSDV DINTEVKSIA VNKKGVYFAF RDQGACISVL AVKVYYITCP
AVTENFAHFN ETPTGREITI IEKQNGTCVD NAEPYETPTY LCKGDGKWTI LTGGCRCKAG
YEPNYTNKTC TECPLGTFKS PEVTKCTPCP PNSNASKTGS PFCKCASGFY RHPNDGRHMP
CYSPPAAPTN LTLLFVDQTS AIISWSAPAK NESFSSETNS KIYHSDIVYK IKCNICSPNV
VYNPSTDTFN ETKITLTNLE PVTTYTVQIH AINSVSHINE FKRHSNESSL VAVSDIVFSN
TSLLNIPLDL NEVKTGQAEI VFTTESVLLS TVFNLRILAI TNKDADLEWD KPVQSDFPLE
FYEVRWFPKV ELDAINKSAL NTKETKAHIV GLLENTEYGF QVRCKTNNGF GSYSNMIYAQ
TLQSVGSVYD DSVQIR
//
