ID E3D767_GARV3 Unreviewed; 2517 AA.
AC E3D767;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=M protein repeat protein {ECO:0000313|EMBL:ADP39237.1};
GN OrderedLocusNames=HMPREF0421_21155 {ECO:0000313|EMBL:ADP39237.1};
OS Gardnerella vaginalis (strain ATCC 14019 / 317).
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Gardnerella.
OX NCBI_TaxID=525284 {ECO:0000313|EMBL:ADP39237.1, ECO:0000313|Proteomes:UP000001453};
RN [1] {ECO:0000313|EMBL:ADP39237.1, ECO:0000313|Proteomes:UP000001453}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14019 / 317 {ECO:0000313|Proteomes:UP000001453};
RX PubMed=20865041; DOI=10.1371/journal.pone.0012411;
RA Yeoman C.J., Yildirim S., Thomas S.M., Durkin A.S., Torralba M., Sutton G.,
RA Buhay C.J., Ding Y., Dugan-Rocha S.P., Muzny D.M., Qin X., Gibbs R.A.,
RA Leigh S.R., Stumpf R., White B.A., Highlander S.K., Nelson K.E.,
RA Wilson B.A.;
RT "Comparative genomics of Gardnerella vaginalis strains reveals substantial
RT differences in metabolic and virulence potential.";
RL PLoS ONE 5:E12411-E12411(2010).
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DR EMBL; CP002104; ADP39237.1; -; Genomic_DNA.
DR RefSeq; WP_013399720.1; NC_014644.1.
DR RefSeq; YP_003986260.1; NC_014644.1.
DR KEGG; gvg:HMPREF0421_21155; -.
DR PATRIC; fig|525284.18.peg.1136; -.
DR HOGENOM; CLU_230234_0_0_11; -.
DR OrthoDB; 3243331at2; -.
DR Proteomes; UP000001453; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1270.90; AF1782-like; 1.
DR Gene3D; 1.20.1270.70; Designed single chain three-helix bundle; 3.
DR Gene3D; 1.20.120.1850; Ebh helix bundles repeating unit (S and A modules); 1.
DR Gene3D; 1.20.5.420; Immunoglobulin FC, subunit C; 4.
DR InterPro; IPR009063; Ig/albumin-bd_sf.
DR Pfam; PF07554; FIVAR; 11.
DR SUPFAM; SSF46997; Bacterial immunoglobulin/albumin-binding domains; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2491..2508
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 78..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1013..1032
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1121..1151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1186..1216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1434..1460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1504..1544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1595..1687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1709..1749
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1764..1787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1816..1851
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1963..1990
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2006..2051
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2112..2153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2219..2247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2280..2307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1057..1115
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1244..1271
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2341..2368
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 78..136
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1122..1136
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1137..1151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1504..1533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1633..1674
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1730..1749
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1817..1850
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2034..2051
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2112..2136
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2280..2306
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2517 AA; 273175 MW; 93E5D7C9C3EC0407 CRC64;
MVSKSRKHAN TVKLDAVVSK AIEKAVDMRK VAALSAGAAG VIAGAAIAFG ATPAMAVEAN
VAPVNTNDST KEQNLVAKKN AEAEGSKDSD KTATETTKKD DASKIEDSKK AEPSAAKNDQ
ADKKVATDKN VAETQDNKSK TEQNLTSSKN ASVQSVVKTD GKKQIENNAE QKKIAEQNTA
STESVDSKTT TNKTPATDKT NATSRTTAEN SAPAETTVKK SRSKRSIYEN KQPETPASTV
AQGEDRAGAE HNPDEVAFSK NLPNIYGWAT PSNTFDENLE KQQVVYHLPK SADGKTVVRV
VILPDSKDSI NTDDPEAYKK IIEFDSARVD EMHQSYSGIY ELKTNTDGSV DLVMKQPFRD
GGISSGQGYC ANRSIFLYYD KDNLQHDQTS NNFRVATLVP PKTAGSIVLK YDERLSADKV
REVLHNAVNL PTEHKSGSSV ADQLVAQSKS AGVGLRVDES TVNNTPDTVD AKIPQGMGSY
DGAMFGEINK TNDSGDYSFG ERKLKTYLVT DLGMKSPEIP LTVVRYSTRI EKPVVDTVDF
SKLTEDQKTQ IRKNLAKLNG VSTDKVTFDS SGTATIDFDG LSPQDDPKIP LSDLVLTRVS
TDKVAIPSDS ENSKVKAVVV ANPLGYSQAE LKQIKKAIYE ANKDNQELGL SAKDYEKQIS
LGWLTGDTTA SGGQNTGISN GMNENKITVT IRTDKAYAQF ESDIQKHELT RLIDLRKDYT
LSWDASNNKI SGRTSDEGLA WMEEGKTLVY RYDPDKGEQI NTQAVLGLLK ATVKSDVKTD
NPQLRENLLG TEIDTVKREG SNGQARRTHR SYTVDDKGEP IGVLNLVKLN GSSYGGFAKP
VDNSNKKMGD EQSSVGDFTF DDDSKKVNVA GKTGKFMLGR LFIEPYSLYY YNYVYGENKY
NLRNTPKGIN VVFVPQTKNK KDDLSKSIGD HKLAADKKTP TESKYYNASA EKKDAYDKAL
DAAKKTLEKV GNKTDADLTE ELKAEVDNAT ITLNKAREAL DGDATKKEEL NKSIEANGKA
PEGATAATPG TVTTDKYKNV TDQAFQTDDG KPDTKKNEAA KAAKKAYDDA LAEAEKVKAD
DNATQKAVDD AKAKLDAARK ELDKYTTNKD KLNAAIAEHG KVNTGDADKQ GDEKLKTADP
TYQNSTSDER TAYDNAVKKA NELSKDPNAS QKDVNKAIED LKKAKDALDK NATDKSPLDA
AVQKSFDNPD PNDDSKQSVF YKNAKNKTND TAAQQAVKNY DDALKKAKDV LANDKATKKD
VEDAKKALEA AETALHSDKY STDKTDLGKA LADNFSGYLM PAYFNAFDKA QADGQDSQAA
KDFKAYNDAY HAAKDLMTEL NKPNSTVTQD EVNKVKDQLI AARKIIDTYA TDTSKLSAAA
FNDIAIKFSP AYQNLKALAE KENPSEAEKA DVEAAKKAKK AYDDAAEKLH NAITNKLPKD
QANGQDIPDS NIPKKDGDHN DKDYLKGIQA HKNGEPLNRD VDTILKEMNE AAKALDKFAT
KTDKLQESIN KDTDTQHDPA YKNAKDPHKL GTDGNEDTSG YNDIKQKAKD YDDALTEAKK
LLTNPTATQA QVDAALKKLD EKRDALKAQD TNVEALKKSV DKNGKDASGT EQAVEGTKDS
DAYRNASDPH FLTADGKPDD TRNNAAKEAK KAYDKALAEA QELLSKHDDT NTPLDAKPTQ
KQIDDALTEL NKKRKALDDY KTNVDALKTE AEKSKADTAQ TVGENDFENT PEFKNADAKK
GEGNKDNDDV TAYKDALKKA RELVKAATDS GKKNSERPTQ KQVDEALEAL KKAKQTITDG
YKTNLDALTA AKDFANGDFK KTPEYKNASA LKDDSSDTQK QSKAKTDVGA LDETTENSAL
KKAKDIIDNP TGKTQKEVDD ALKTLQAAMD TVTNGYKTVV DPLEKEVGDK DATGKPITPP
FEESIPYKNA LYKKQSETGN DATADTSATK KLQDYNEKFK AAQDLINKVN NPDPNADSDK
KPTNADVKTA LEALQKAKKA IDDAFTTSAK DLKDESAKST ADGGTVADAD FEATTEFKNA
DSKKAEDGKS DNADISAYKE ALKKARTLLE KFGDDNKPKS DAKDVPTQKE VDEALKKLKE
IKDKILADYK TSSTELQQEV DKSKDGDKDT RDDVFENTPA FKNATAKGDE DSKKALEDYN
TKLKTARDLL KAFDRTTGKP KTKLPEGVTT VPTQKQLYDA LDALQAAKKK ITEGYKTDKS
DLNTEAGKDS DFTKSPEYQN AAGSSEAEAY KRALDEANAV LKNPNATQAE VDEALKKLQD
AKQKLTDSHK TDKSDLNTEA DNDPDFRKSI PFIIGKAADL AEYQQALNDA DSVLKDPNAT
QDQVNQALRR LRDAKQKLID AYNRLINSGS GVGDNTGVGV NDSNTTSVNN VVDKSALQAE
VDQALGDVSA NASGVVADSN LVSEFNAALN YARLVLADAN ATQGQVDSAL ARLRAARAAL
REGMLAARNS AGVNLKRGDV SGVNTGASSS VFAALAAVFA GLGVAGAASK RRKHSAR
//
