ID E3EFZ4_PAEPS Unreviewed; 1189 AA.
AC E3EFZ4;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Chromosome partition protein Smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN Name=smc {ECO:0000256|HAMAP-Rule:MF_01894,
GN ECO:0000313|EMBL:ADO56027.1};
GN ORFNames=PPSC2_09695 {ECO:0000313|EMBL:ADO56027.1};
OS Paenibacillus polymyxa (strain SC2) (Bacillus polymyxa).
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=886882 {ECO:0000313|EMBL:ADO56027.1, ECO:0000313|Proteomes:UP000006868};
RN [1] {ECO:0000313|EMBL:ADO56027.1, ECO:0000313|Proteomes:UP000006868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC2 {ECO:0000313|EMBL:ADO56027.1,
RC ECO:0000313|Proteomes:UP000006868};
RX PubMed=21037012; DOI=10.1128/JB.01234-10;
RA Ma M., Wang C., Ding Y., Li L., Shen D., Jiang X., Guan D., Cao F.,
RA Chen H., Feng R., Wang X., Ge Y., Yao L., Bing X., Yang X., Li J., Du B.;
RT "Complete genome sequence of Paenibacillus polymyxa SC2, a strain of plant
RT growth-promoting Rhizobacterium with broad-spectrum antimicrobial
RT activity.";
RL J. Bacteriol. 193:311-312(2011).
CC -!- FUNCTION: Required for chromosome condensation and partitioning.
CC {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC each terminus and a third globular domain forming a flexible hinge near
CC the middle of the molecule. These domains are separated by coiled-coil
CC structures. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
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DR EMBL; CP002213; ADO56027.1; -; Genomic_DNA.
DR RefSeq; WP_013370642.1; NC_014622.2.
DR AlphaFoldDB; E3EFZ4; -.
DR STRING; 1406.LK13_22160; -.
DR KEGG; ppm:PPSC2_09695; -.
DR PATRIC; fig|886882.15.peg.2043; -.
DR eggNOG; COG1196; Bacteria.
DR HOGENOM; CLU_001042_2_2_9; -.
DR OrthoDB; 9808768at2; -.
DR Proteomes; UP000006868; Chromosome.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd03278; ABC_SMC_barmotin; 2.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01894; Smc_prok; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR InterPro; IPR011890; SMC_prok.
DR NCBIfam; TIGR02168; SMC_prok_B; 1.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|HAMAP-
KW Rule:MF_01894};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01894};
KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Reference proteome {ECO:0000313|Proteomes:UP000006868}.
FT DOMAIN 521..640
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT COILED 167..201
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 262..296
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 332..483
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 682..828
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 878..926
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT BINDING 32..39
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
SQ SEQUENCE 1189 AA; 135090 MW; E8103D313F81294C CRC64;
MFLKRIELAG FKSFADKTEM EFVRGITAVV GPNGSGKSNI SDGIRWVLGE QSAKSLRGGK
MEDIIFAGSD ARKAVNYGEV SLTLDNEDQA LPLDFGEVTV TRRVHRSGDS EYFINRQSCR
LRDITELFMD TGIGKEAYSI IGQGRIEEIL STRSEDRRGI FEEASGIVKY KSRKKDAVRK
LDETEQNLLR IHDLVSELED QIGPLKEQSE KAIHFKELRS ELKSKEISMY VHQIEQIHTS
WSDATSKLAL LQQEQLQLST VVSRHDAMLE NDRNELRQLE EQVERLQKDL LQYSEATEKS
EGYGELLKER TRNLEANREQ LILSLSTSES RHSERKSELD QLNEKLSALN VELDELRARL
SDEEAKLIGV TGGISQEQEE SLKGGLLELM NQMAQARNEI RYTDQQKEAL ERRVNRVSDE
SGKWEAQKVE LEQRKKGLEA TIQKLGQEIS SLRSGYIQGS EQYQALQKLL EENQGTVRKW
EQKREAQISR RDTMKEMQDD FDGFMLGVKE VLKASRKGTL HGVHGAVAEL IRVPEHLEQA
METALGASVQ HIVMENESVS RQAISFLKQR QLGRATFLPM DVIRPRQIGA GERQIVESAE
GFVGIGADLV QYDDRYAGIV GSLLGNVVIA RTLEDANRIA ARCQYRYRVV TLEGDVVNAG
GSMTGGSQFK KNANLLGRKR QLDQLDQDIL DTEQQIARLR QSAIDTKRQL EETQTRLDEL
RQGGDVKRTE EQQMAMELKQ LEHELRHVLE QVAASGQEKK GFDQEIKELE ASRAEALVKL
AALEEEEKKT HQAIHAAEFA RKANESAKEQ LQGELTNLKV REGKLDQERF SLEEQIRRLR
GDYDTLGKDS RQNKTLLASI EADLLTNEQE TVKQIENLNQ YRLKKEEAAE QLEFKRAARS
SLSKKLEVAE NDTKEQRIQL KSVEELLRQT EIGVNRLDVE LENVLKKLSD DYELSYELAK
QRYPIPEDIE GTQSEVERLK RGISALGEVN LGAIEEYQRV HERYTFLDEQ KSDLVEAKTT
LYQVIREMDD EMSKRFKTTF DAIRREFGTV FSKLFGGGRA DLVLLDPERL LETGIDIVAQ
PPGKKLQNLQ LLSGGERALT AMALLFAILH VKPVPFCVLD EVEAALDEAN VVRFAQYLRE
FSEQTQFIVV THRKGTMEES DVLYGVTMEE GGVSKLVSVK LDNDEAEIA
//
