ID E3G894_ENTLS Unreviewed; 1071 AA.
AC E3G894;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Aldehyde oxidase and xanthine dehydrogenase molybdopterin binding protein {ECO:0000313|EMBL:ADO49762.1};
GN OrderedLocusNames=Entcl_3518 {ECO:0000313|EMBL:ADO49762.1};
OS Enterobacter lignolyticus (strain SCF1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Pluralibacter.
OX NCBI_TaxID=701347 {ECO:0000313|EMBL:ADO49762.1, ECO:0000313|Proteomes:UP000006872};
RN [1] {ECO:0000313|Proteomes:UP000006872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCF1 {ECO:0000313|Proteomes:UP000006872};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N.,
RA Mikhailova N., DeAngelis K., Arkin A.P., Chivian D., Edwards B., Woo H.,
RA Hazen T.C., Woyke T.;
RT "Complete sequence of Enterobacter cloacae SCF1.";
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADO49762.1, ECO:0000313|Proteomes:UP000006872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCF1 {ECO:0000313|EMBL:ADO49762.1,
RC ECO:0000313|Proteomes:UP000006872};
RX PubMed=22180812; DOI=10.4056/sigs.2104875;
RA Deangelis K.M., D'Haeseleer P., Chivian D., Fortney J.L., Khudyakov J.,
RA Simmons B., Woo H., Arkin A.P., Davenport K.W., Goodwin L., Chen A.,
RA Ivanova N., Kyrpides N.C., Mavromatis K., Woyke T., Hazen T.C.;
RT "Complete genome sequence of "Enterobacter lignolyticus" SCF1.";
RL Stand. Genomic Sci. 5:69-85(2011).
CC -!- COFACTOR:
CC Name=Mo-molybdopterin; Xref=ChEBI:CHEBI:71302;
CC Evidence={ECO:0000256|ARBA:ARBA00001924};
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
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DR EMBL; CP002272; ADO49762.1; -; Genomic_DNA.
DR RefSeq; WP_013367488.1; NC_014618.1.
DR AlphaFoldDB; E3G894; -.
DR STRING; 701347.Entcl_3518; -.
DR KEGG; esc:Entcl_3518; -.
DR eggNOG; COG1319; Bacteria.
DR eggNOG; COG1529; Bacteria.
DR HOGENOM; CLU_001681_2_3_6; -.
DR Proteomes; UP000006872; Chromosome.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.90.1170.50; Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; 1.
DR Gene3D; 3.30.365.10; Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain; 4.
DR Gene3D; 3.30.390.50; CO dehydrogenase flavoprotein, C-terminal domain; 1.
DR Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR InterPro; IPR000674; Ald_Oxase/Xan_DH_a/b.
DR InterPro; IPR036856; Ald_Oxase/Xan_DH_a/b_sf.
DR InterPro; IPR016208; Ald_Oxase/xanthine_DH-like.
DR InterPro; IPR008274; AldOxase/xan_DH_MoCoBD1.
DR InterPro; IPR046867; AldOxase/xan_DH_MoCoBD2.
DR InterPro; IPR037165; AldOxase/xan_DH_Mopterin-bd_sf.
DR InterPro; IPR005107; CO_DH_flav_C.
DR InterPro; IPR036683; CO_DH_flav_C_dom_sf.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR002346; Mopterin_DH_FAD-bd.
DR PANTHER; PTHR11908:SF132; ALDEHYDE OXIDASE 1-RELATED; 1.
DR PANTHER; PTHR11908; XANTHINE DEHYDROGENASE; 1.
DR Pfam; PF01315; Ald_Xan_dh_C; 1.
DR Pfam; PF03450; CO_deh_flav_C; 1.
DR Pfam; PF00941; FAD_binding_5; 1.
DR Pfam; PF02738; MoCoBD_1; 1.
DR Pfam; PF20256; MoCoBD_2; 1.
DR SMART; SM01008; Ald_Xan_dh_C; 1.
DR SMART; SM01092; CO_deh_flav_C; 1.
DR SUPFAM; SSF55447; CO dehydrogenase flavoprotein C-terminal domain-like; 1.
DR SUPFAM; SSF54665; CO dehydrogenase molybdoprotein N-domain-like; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF56003; Molybdenum cofactor-binding domain; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW 2Fe-2S {ECO:0000256|ARBA:ARBA00022714};
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022827};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006872}.
FT DOMAIN 782..957
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
SQ SEQUENCE 1071 AA; 116637 MW; CB0C7956F0802A63 CRC64;
MCASRSAPLR RVDGLAKVKG TAIYGDDITL PGMLYGVCRF ADIPAGKIEE IDLSEALSVE
GVVKIATWQD IPGTPAVGII VKDYLPIVKD EVVFHGDVVA VVAATSYEVA CEAADKIRVR
YAPYVPLTDV EEAMAPDARR IHPECRDNVV AHHHTVKGDI EKGFAEAKHV IEREYEVGFQ
EHAYIEPEVV LTWLDPTDGS LIISGSIQNP HRVRSFVAKF IGCPQSQINV KRAVMGGSFG
GKDDIIDHLA CRSALMTRLT GCPVKFTYTR EQSIIESCKR HPYKMKYRAG MDDAGRILAI
KIDILADSGG YAASSPFVTW RSSVQAAGPY NIPNVHIDVK AVYTNNSYTS AMRGFGSPQV
VYANESFMDE IAETLNLSPV AVREVNALRQ GDTSVTGQLF DKHTVSAVEV LNKAVNASEF
AARRQHYREL NLKGGVYRYG IGIALSYRGC SIGAEGVDTS TALIQVNEDG SVNLATSVSE
NGQGLQTAMS LIAAETFGIE LADLHFMEPP TSVIGDGGST AATRGTMVGG GAILDAADKI
KRRILSVVGD SIGTRELSET RWQNGFIINI QDSERRIDFK TAVNKTKWAS VSLTEYGWFV
PPPIHWDEEK GCGSPYFTWV YGCQVAEVRV NTSTGKTDLL HVTAAHDVGR VLNPVGFEGQ
VYGGVAQGFG YALLEDFNIE NGQVKSENFD SYLLPTMKDI PRMTVIGVEN PDIAGPLGAK
GIGEPATELA AAAINNAVSF ALEARFNKLP LTLEQVILGY NLKKPVRQSE MMLEAENRKH
VLRLTDVEVT RPQSLQEALT LLANDGVTAI AGGTDVIVQG RLQTRAMRLI DISHLPELTQ
VSEDPATHEV TIGGAMTFNR ITDHPLLRER YPLLVQACHT VGSHQIRNRA TIGGNIVNAA
PCGDSIPPAI LYDARIELCS LNGMRTLGLA EFLLSGYKTQ RQPDELLTKV ILPPPARPQA
KGFYHQLGRR NALNITRQSL SALLDFADDG TVSYCRLVDG ALFSKPQRLL DIERCLLGKP
LNSDSINSAC EVLDKLIYAA IGKRWSAAYK QPVFVNMFRD MMAEAQQVSG I
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