ID E3HP79_ACHXA Unreviewed; 372 AA.
AC E3HP79;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=CobW/HypB/UreG, nucleotide-binding domain protein 5 {ECO:0000313|EMBL:ADP19548.1};
GN OrderedLocusNames=AXYL_06255 {ECO:0000313|EMBL:ADP19548.1};
OS Achromobacter xylosoxidans (strain A8).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Achromobacter.
OX NCBI_TaxID=762376 {ECO:0000313|EMBL:ADP19548.1, ECO:0000313|Proteomes:UP000006876};
RN [1] {ECO:0000313|EMBL:ADP19548.1, ECO:0000313|Proteomes:UP000006876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A8 {ECO:0000313|EMBL:ADP19548.1,
RC ECO:0000313|Proteomes:UP000006876};
RX PubMed=21097610; DOI=10.1128/JB.01299-10;
RA Strnad H., Ridl J., Paces J., Kolar M., Vlcek C., Paces V.;
RT "Complete genome sequence of the haloaromatic acids-degrading bacterium
RT Achromobacter xylosoxidans A8.";
RL J. Bacteriol. 193:791-792(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; CP002287; ADP19548.1; -; Genomic_DNA.
DR RefSeq; WP_013396836.1; NC_014640.1.
DR AlphaFoldDB; E3HP79; -.
DR STRING; 762376.AXYL_06255; -.
DR KEGG; axy:AXYL_06255; -.
DR PATRIC; fig|762376.5.peg.6270; -.
DR eggNOG; COG0523; Bacteria.
DR HOGENOM; CLU_017452_0_0_4; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000006876; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 276..370
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 232..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 372 AA; 41833 MW; 73CA632A237778AB CRC64;
MNTPRSLDKM VPVTILTGFL GAGKTTLLKR ILTEYHGRRV AVIENEFGPE SIDNDLLVQD
SNEEIIELSN GCVCCTVRGD LMRTLSELRA KREAGELNFE RVILETTGMA NPGPVCQTFF
MDDDIAEYYR LDAVVTVVDA KHGMATLDAQ PEAQKQVGFA DRILISKRDL VNEVDYEALR
HRLVHMNPRA PITPVNFGEV DLKSIIDISG FNLNSILDID PQFLADEHPD AAHDHVHDHD
HGHDHGHDHD HDHEGDCGAH CNHAHHHHHH QHDDEIGAFV FRSNKPFDPA RLEEFLGGVV
QVYGPDLMRY KGILYMKGIN RRMLFQGVHM MMGAEPGKPW TAAEKPSTKM VFIGRKLPQE
IFTRGLEQCL AG
//
