ID E3I7L7_RHOVT Unreviewed; 786 AA.
AC E3I7L7;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=ATP-dependent Clp protease, ATP-binding subunit clpA {ECO:0000313|EMBL:ADP69633.1};
GN OrderedLocusNames=Rvan_0347 {ECO:0000313|EMBL:ADP69633.1};
OS Rhodomicrobium vannielii (strain ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG
OS 4299).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Hyphomicrobiaceae; Rhodomicrobium.
OX NCBI_TaxID=648757 {ECO:0000313|EMBL:ADP69633.1, ECO:0000313|Proteomes:UP000001399};
RN [1] {ECO:0000313|Proteomes:UP000001399}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG 4299
RC {ECO:0000313|Proteomes:UP000001399};
RX PubMed=21705585; DOI=10.1128/JB.05453-11;
RG US DOE Joint Genome Institute;
RA Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.;
RT "Genome sequences of eight morphologically diverse alphaproteobacteria.";
RL J. Bacteriol. 193:4567-4568(2011).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
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DR EMBL; CP002292; ADP69633.1; -; Genomic_DNA.
DR RefSeq; WP_013418040.1; NC_014664.1.
DR AlphaFoldDB; E3I7L7; -.
DR STRING; 648757.Rvan_0347; -.
DR KEGG; rva:Rvan_0347; -.
DR eggNOG; COG0542; Bacteria.
DR HOGENOM; CLU_005070_4_2_5; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000001399; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0043335; P:protein unfolding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR013461; ClpA.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02639; ClpA; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF111; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:ADP69633.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:ADP69633.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001399};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..148
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT REGION 765..786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 786 AA; 86754 MW; D5D1D483B394E0DB CRC64;
MPSFSNSLEE SLHRAIEYAN ERHHEYATLE HLLLSLLDDR DASSVLRACN VDVERLRAKL
TEFLDKELNN LVLDQDGEAQ PTASFQRVIH RAVVHVQSSG REEVTGANVL VAVFAERESN
AAYFLQEQDM TRFDAVNFIS HGISKRAGMS EPRGVRGVED DATTVDGAEE KKRSTDALEA
YCVNLNQKAK DGRIDPLIGR DKEIERTIQV LCRRSKNNPL YVGDPGVGKT AIAEGLARKI
VRGEVPQVLA NATVFSLDMG TLLAGTRYRG DFEERLKAVM KEIEAYPGAI LFIDEIHTVI
GAGATSGGAM DASNLLKPAL QSGVLRCIGS TTYKEYRQHF EKDRALVRRF QKIDVAEPTV
EDAIEIMKGL KPYFEDFHNI KYTNQAIKAA VELSAKYIHD RKLPDKAIDV IDETGASQML
LAPSKRKRTI GVKEVEATVA TMARIPPKTV SKTDTELLRN LEGDLRRVVF GQDQAIHALS
AAIKLARAGL RDAEKPIGSY LFSGPTGVGK TEVARQLASL LGVQILRFDM SEYMERHTVS
RLIGAPPGYV GFDQGGLLTD GVDQNPHCVL LLDEIEKAHP DLFNVLLQVM DHGKLTDHNG
KQVDFRNVVL IMTTNAGAAD MAKPAIGFGS QQRVGEDEEA IKRMFSPEFR NRLDAVIPFA
RLSREMIGRV VEKFIFQLEA QLADRNVIIE LTPEAMEWLA DHGYDEMYGA RPLARVIQES
IKKPLAEELL FGKLEGGGTV RVVVEEKDGQ KQLAFEVIEA KPPVVKAEDA EASEGDGPAL
LPKGAA
//
