ID E3LA22_PUCGT Unreviewed; 678 AA.
AC E3LA22;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=ATP-dependent DNA helicase sgs1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=PGTG_19415 {ECO:0000313|EMBL:EFP93397.2};
OS Puccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL)
OS (Black stem rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=418459 {ECO:0000313|EMBL:EFP93397.2, ECO:0000313|Proteomes:UP000008783};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CRL 75-36-700-3;
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Cuomo C., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Mauceli E., Brockman W.,
RA Young S., LaButti K., Sykes S., DeCaprio D., Crawford M., Koehrsen M.,
RA Engels R., Montgomery P., Pearson M., Howarth C., Larson L., White J.,
RA Zeng Q., Kodira C., Yandava C., Alvarado L., O'Leary S., Szabo L., Dean R.,
RA Schein J.;
RT "The Genome Sequence of Puccinia graminis f. sp. tritici Strain CRL 75-36-
RT 700-3.";
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000008783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRL 75-36-700-3 / race SCCL
RC {ECO:0000313|Proteomes:UP000008783};
RX PubMed=21536894; DOI=10.1073/pnas.1019315108;
RA Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E.,
RA Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J., Cantarel B.L.,
RA Chiu R., Coutinho P.M., Feau N., Field M., Frey P., Gelhaye E.,
RA Goldberg J., Grabherr M.G., Kodira C.D., Kohler A., Kuees U.,
RA Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E., Murat C.,
RA Pangilinan J.L., Park R., Pearson M., Quesneville H., Rouhier N.,
RA Sakthikumar S., Salamov A.A., Schmutz J., Selles B., Shapiro H.,
RA Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y., Rouze P.,
RA Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C.,
RA Grigoriev I.V., Szabo L.J., Martin F.;
RT "Obligate biotrophy features unraveled by the genomic analysis of rust
RT fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011).
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; DS178391; EFP93397.2; -; Genomic_DNA.
DR RefSeq; XP_003337816.2; XM_003337768.2.
DR AlphaFoldDB; E3LA22; -.
DR STRING; 418459.E3LA22; -.
DR EnsemblFungi; EFP93397; EFP93397; PGTG_19415.
DR GeneID; 10537264; -.
DR KEGG; pgr:PGTG_19415; -.
DR VEuPathDB; FungiDB:PGTG_19415; -.
DR HOGENOM; CLU_011478_1_1_1; -.
DR InParanoid; E3LA22; -.
DR OrthoDB; 5405140at2759; -.
DR Proteomes; UP000008783; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0009378; F:four-way junction helicase activity; IBA:GO_Central.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006268; P:DNA unwinding involved in DNA replication; IBA:GO_Central.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR CDD; cd14686; bZIP; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008783}.
FT DOMAIN 85..251
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 291..440
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 645..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..678
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 678 AA; 76614 MW; 88CFD290CE88F09D CRC64;
MAIFKEKRGK KVHTPTTSSI KSTRNPPKRV IKKTTSHPPK QLNTGVTICK KLMNANDDAL
KKEIASRARN FYNGEEAKTL QIDVVANLAR GRNTFLLAGT GYGKSRISEM YFKLLPQNTK
PVILVLNPLD ALGENQVAEK QGKFSAINLT KLTFNKNEAD KIQRGDYNFV YLSPEIFMNN
KLWDSIYFST EFQQRLALVV VDEAHMIYLW GLVETLHLQS RNNAPLLMLS ATCRPVAIDA
ILKSLKLTED LIDIKRGELS RKEIRIIHIK MDCSLQSSLD LLNVFPTKQK TSDEDLVPTL
IYSGTRARTF TVLQVLDMAR GTPQNCLDPN NTLARRFHAC TGDKDKVDVV EGFSKGQFPI
ISSTMALGLG QNWKRVRCVI HMGRADPENV MQMIGRCGRD GKDGLAILFV EGNRKGGKNA
INDFVNVQNQ SDDDRMDALA ITPVCLRVAF AIDNKHGYIP LSKTDSNYIA EIDREKLCQF
PPCRCSNCNV ESGMKLIENL KELSIHNFDD AMNDRAEFTH VSNGQTSVKR KQTRCGKTLL
GGEAGKEIVV KFKECLLSSF REYYNNRKAR SCRFSAHDVF REEHADAIIA NLDNLDDLDS
LERIVGGEVI EGQIEFILNS IASFKIGSDY QNHLKNQERL KEEVEEARKK KRRESAARYR
AKKKAMLEEA RAKQHKSN
//
