ID   E3LTL9_CAERE            Unreviewed;       692 AA.
AC   E3LTL9;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   24-JAN-2024, entry version 57.
DE   SubName: Full=CRE-CRM-1 protein {ECO:0000313|EMBL:EFP11251.1};
GN   Name=Cre-crm-1 {ECO:0000313|EMBL:EFP11251.1};
GN   ORFNames=CRE_30665 {ECO:0000313|EMBL:EFP11251.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS268415; EFP11251.1; -; Genomic_DNA.
DR   RefSeq; XP_003112730.1; XM_003112682.1.
DR   AlphaFoldDB; E3LTL9; -.
DR   STRING; 31234.E3LTL9; -.
DR   EnsemblMetazoa; CRE30665.1; CRE30665.1; WBGene00059133.
DR   GeneID; 9824022; -.
DR   KEGG; crq:GCK72_017532; -.
DR   CTD; 9824022; -.
DR   eggNOG; KOG1216; Eukaryota.
DR   HOGENOM; CLU_028701_0_0_1; -.
DR   InParanoid; E3LTL9; -.
DR   OMA; LYGFETN; -.
DR   OrthoDB; 2946817at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   Gene3D; 6.20.200.20; -; 4.
DR   InterPro; IPR004094; Antistasin-like.
DR   InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR   InterPro; IPR011061; Hirudin/antistatin.
DR   InterPro; IPR000867; IGFBP-like.
DR   InterPro; IPR001007; VWF_dom.
DR   PANTHER; PTHR46439; CYSTEINE-RICH MOTOR NEURON 1 PROTEIN; 1.
DR   PANTHER; PTHR46439:SF1; CYSTEINE-RICH MOTOR NEURON 1 PROTEIN; 1.
DR   Pfam; PF02822; Antistasin; 3.
DR   Pfam; PF00093; VWC; 4.
DR   SMART; SM00214; VWC; 4.
DR   SUPFAM; SSF57603; FnI-like domain; 4.
DR   SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR   SUPFAM; SSF57262; Leech antihemostatic proteins; 1.
DR   PROSITE; PS51252; ANTISTASIN; 3.
DR   PROSITE; PS51323; IGFBP_N_2; 1.
DR   PROSITE; PS01208; VWFC_1; 3.
DR   PROSITE; PS50184; VWFC_2; 4.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..692
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003175432"
FT   DOMAIN          24..92
FT                   /note="IGFBP N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51323"
FT   DOMAIN          262..321
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          318..379
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          390..416
FT                   /note="Antistasin-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51252"
FT   DOMAIN          427..455
FT                   /note="Antistasin-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51252"
FT   DOMAIN          458..484
FT                   /note="Antistasin-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51252"
FT   DOMAIN          516..581
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          601..661
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
SQ   SEQUENCE   692 AA;  76298 MW;  FD71A01124FBC8E1 CRC64;
     MKCAFSLLFF SVLFIVSNAK TEKTTVSCGS CEKETCPEVS GCAKLKMDQC DCCQICVRQV
     NESCGEPGLV CDSHLSCDQE NDLDGSSRCK ERMHEECLKA ICPVVFHRGC PSDSQLITER
     PAPGKCCPPP GTCHCDQKKC VPSVPTCTKE ERLVMTEKGS ETPGECCAKY ECQKKEKKCD
     NVHCPPMIQD EEECPSDSFR PPETIPKESC CPVRQSCKCR GSICRPAQCP DGQVIHVTKK
     GTGYPGRCCD DWECIEGETS KAKCYYNGVE RQPMEVWHAN DCDTCQCIKG VSICDKGDCP
     KVNQECTWIG IPTGECCPIC LGCQTDNQTK LERGATWQKD DCTSCTCSEL GAHMCEKYMC
     KTDCENPRKV EGQCCPVCDE PTIIRPPATC PSLELCSLRC ANGLRRDNIG CYVCECLPDE
     VPTNPRCREL NDENCEKQCA HGYLKDEDGC TVCKCSKCPP LHQCHKHCLY GFETNSAGCS
     LCKCRASSKL DKKPNTTKST KTGGAGSSQM TEYHSEKCIS FSNDGHQIVR DGGEWWSDGC
     RHCFCENKQE FCSLISCPTK PSDCADENWV QKEDECCPSC TDQKKKPKSS NSLAAQKHEH
     TVCQSPGTGR LFTDGETWQL APCVSCTCRV GHVLCRTTEC PPIACPNPEY ENEDDCCPTC
     PEQKVVNTKN EKGDTIVCTD DSGTAHIVGK FS
//