ID E3M2F0_CAERE Unreviewed; 356 AA.
AC E3M2F0;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=nicotinamidase {ECO:0000256|ARBA:ARBA00039017};
DE EC=3.5.1.19 {ECO:0000256|ARBA:ARBA00039017};
DE AltName: Full=Nicotinamide deamidase {ECO:0000256|ARBA:ARBA00043224};
GN ORFNames=CRE_07442 {ECO:0000313|EMBL:EFO89637.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; nicotinate biosynthesis; nicotinate
CC from nicotinamide: step 1/1. {ECO:0000256|ARBA:ARBA00037900}.
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
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DR EMBL; DS268422; EFO89637.1; -; Genomic_DNA.
DR RefSeq; XP_003109495.1; XM_003109447.1.
DR AlphaFoldDB; E3M2F0; -.
DR STRING; 31234.E3M2F0; -.
DR EnsemblMetazoa; CRE07442.1; CRE07442.1; WBGene00073155.
DR eggNOG; KOG4003; Eukaryota.
DR HOGENOM; CLU_779008_0_0_1; -.
DR InParanoid; E3M2F0; -.
DR OrthoDB; 47357at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR PANTHER; PTHR11080:SF31; ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11080; PYRAZINAMIDASE/NICOTINAMIDASE; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridine nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022642};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281}.
FT DOMAIN 30..126
FT /note="Isochorismatase-like"
FT /evidence="ECO:0000259|Pfam:PF00857"
FT REGION 236..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 39789 MW; 012FE4DE6968922D CRC64;
MIQKLRPSVS KELTTSKKGR MSTWMLTVLY PSHCIQGGWG SQLHLGLQRV KGAHYIKKGA
DVYVDAYRAF SDNCGIKQSE LEMLLRKNDI NAVIGCGLAY DICVMHTLKD ASKHGFLTCI
VKSGRSSSIL TPVSQSKTGH LKDFVAPRIG RQSRPTMKTE HTVHFFQKNI IHSSTGQRRP
VMETPVADTN IVPTLPPHCK AESRTLRTTL CNQQGQRNQG AAQQPLLLAG SLSLHRETSN
SRMPPGQTKT CGRQSTTPTS SNGRLHKELS SLKMDEANKM FQKRGVAIID DEMAQLISKR
EAFPIEWVKE DFNVFRGVKK KLEHSETQKD SFILTSLISI NLFTRLRFPK LSVSAT
//
