ID E3MEM2_CAERE Unreviewed; 419 AA.
AC E3MEM2;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
GN ORFNames=CRE_21750 {ECO:0000313|EMBL:EFP00445.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|RuleBase:RU361203};
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC acid phosphatase family. {ECO:0000256|RuleBase:RU361203}.
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DR EMBL; DS268439; EFP00445.1; -; Genomic_DNA.
DR RefSeq; XP_003105387.1; XM_003105339.1.
DR AlphaFoldDB; E3MEM2; -.
DR STRING; 31234.E3MEM2; -.
DR EnsemblMetazoa; CRE21750.1; CRE21750.1; WBGene00061338.
DR GeneID; 9816752; -.
DR KEGG; crq:GCK72_012140; -.
DR CTD; 9816752; -.
DR eggNOG; KOG1378; Eukaryota.
DR HOGENOM; CLU_013387_5_0_1; -.
DR InParanoid; E3MEM2; -.
DR OMA; MPRNGVY; -.
DR OrthoDB; 203742at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00839; MPP_PAPs; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041792; MPP_PAP.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR InterPro; IPR015914; Purple_acid_Pase_N.
DR InterPro; IPR025733; Purple_acid_PPase_C_dom.
DR PANTHER; PTHR45867; PURPLE ACID PHOSPHATASE; 1.
DR PANTHER; PTHR45867:SF2; PURPLE ACID PHOSPHATASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF14008; Metallophos_C; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|RuleBase:RU361203};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361203}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT CHAIN 20..419
FT /note="Purple acid phosphatase"
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT /id="PRO_5005127865"
FT DOMAIN 23..116
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
FT DOMAIN 125..325
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 350..412
FT /note="Iron/zinc purple acid phosphatase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14008"
SQ SEQUENCE 419 AA; 47943 MW; 5051C5983D6D57B4 CRC64;
MILRLTFCLL AIAAATVCSK KVEQVHLSLS GRPDEMVVTW LTLDPLPNVT PYVAFGVTKN
SLRLTAKGNT TGWADQGKKG KMRYTHRATM QNMVAGQLYY YQVGSSQEMS EIFHFRQPDQ
SQPLRAAIFG DLSIYKGQQS IDQLIAARKD NQFDLIIHIG DLAYDLHDQD GSTGDDYMNA
IEPFAAYVPY MVFAGNHEVD SNFNHITNRF TMPRNGVYDN NLFWSFDYGF VHFIALNSEY
YAEEMSKESQ KQFKWLEQDL ANNKKKWTIV MFHRPWYCSS KKKKGCHDDE DILSREGLTD
KFPGLEELLN QHKVDLILYG HKHTYERMWP IFNKEPFKSS DPTHIKNAPA PVYILTGGAG
CHSHEDPSDH IIQDFSVKAL GEYGYTFLTV YNATHLSTDF VDTSETTGKF LDPFVLEKN
//
