ID   E3MJ71_CAERE            Unreviewed;      1441 AA.
AC   E3MJ71;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN   ORFNames=CRE_09591 {ECO:0000313|EMBL:EFP03442.1};
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN   [1] {ECO:0000313|Proteomes:UP000008281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG   Caenorhabditis remanei Sequencing Consortium;
RA   Wilson R.K.;
RT   "PCAP assembly of the Caenorhabditis remanei genome.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS268449; EFP03442.1; -; Genomic_DNA.
DR   RefSeq; XP_003103851.1; XM_003103803.1.
DR   STRING; 31234.E3MJ71; -.
DR   EnsemblMetazoa; CRE09591.1; CRE09591.1; WBGene00059690.
DR   eggNOG; KOG1075; Eukaryota.
DR   HOGENOM; CLU_251853_0_0_1; -.
DR   InParanoid; E3MJ71; -.
DR   OrthoDB; 5402748at2759; -.
DR   Proteomes; UP000008281; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd01650; RT_nLTR_like; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR021942; DUF3557.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR33395:SF21; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR33395; TRANSCRIPTASE, PUTATIVE-RELATED-RELATED; 1.
DR   Pfam; PF12078; DUF3557; 1.
DR   Pfam; PF14529; Exo_endo_phos_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   PRINTS; PR01345; CERVTRCPTASE.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008281}.
FT   DOMAIN          972..1218
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   REGION          439..485
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          514..541
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        452..473
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1441 AA;  165690 MW;  51E94C234FC9A945 CRC64;
     MPPGLTYPSL KCVFEFLEAN KRIHITSRNS NLKIVDKLVP LRLKMLQIDG RLIMVNYVAY
     RVLDVNEPED SFGNDFERFY SNPQYGRQIP RGYFPIFYQK NGTGNTKYEY ENRRGKIFRR
     RIRKDYHSEK LKHVITFHFL ILRLLESLFV GRRVIIVEKL VTGWLLPLSK KLELKFNILE
     LESDGYDLKG FVPLIDPTSF PLKKLTQKPS LYTLFEHPEV RTASHLVIKE FFPNLSNAIN
     ILKSLNCKYI EIKDLLFNQN YILDTIQMLL ENHRDVETCY MIDTVSVRII YTSEYTGNFM
     KRIKERFVGR YVDFMDAEKR STLTSQYVSI PVDSRTELAV YRNKSLKERQ EVVIMEVILT
     GHIPKVFRLD YSKSEYILSP DARFSTTSKK RFHFIWIICI SSAMKISLFN FFSLFNFFSS
     RAVVSRGALM KRFLNFSPTE KSTDKRSKSL SETNSIDSLN SSNSTITEMS ALPPNPTPTT
     PTPNLSDSVA KLHNLKKINM DEFSKLILSM ANVIGVLQKQ NNTLIAEVRN LTTEISNLKN
     TVVAAPTNNK KTFADMVRKS LTAPAAQVSI LRAAELAQTC DARKSCVIVR NADLASDTSE
     DNDFGVKVAK ECVDIMAGGV SIRIVVGYHP SHHSKLDGMI SCLEFLLSTR KNCVILGDFN
     MPHISWPSLT ASDSHCKKFL SFVTKNGLTQ HIASPTRLKP DNILDLCFTN TDVLRDVRVG
     DLFSDHKLIH VTLSVKNRTK KLTKEVKLFR KADYASINYL LSNTDWVLRF SNLNADGMYE
     NLLSILHELI ASYVPVKAIN TLSKRHSAEI LKLQKAKLNV WRKEGNSTNY KNISADLKVA
     LIKEERRVND EKLTNGSVKD FFKFINSRYK DNQEIGTLKN DSGAPINCDS EKVELFSDSF
     LKVFTEDNNI QPHFDKRTEE LVSSPDFEPY IIEHTLSKIT PKLNTTPDGI PALFLKNVCT
     AIALPLSIIF RESFRTSIVP TAWKTAIVKP LHKKGSRANP NNYRPISLTS SVGKVMEKLV
     RKQLTNYLNS NRLLSNCQYG FRSSMSTEAQ LLSYQADILT NYICKKTTHS VYIDFKKAFD
     KVSLSKLKIK LRSYGIHDDF FNWLCAFLTN RTQRVCINNV FSSDRSVLSG VPQGSVLGPL
     LFLLFINDIG DAFESNYLLY ADDLKLFSTN ADCIKKDLVR LSVWCDNWQM GVAPEKCEVI
     SFNHSKKHSN SASLNFSIND AIIPQTKIIR DLGIIFNSDL NFSNHLDVTL RKAHQRVNIF
     FNVLRHADFE IFIKCFKIYV RPLLEYGSTV FSPTSKEQVR LIESVQKTFI FRVFRKFNIP
     YISYFESIKH CDILSLEHRR IIIDLVFMYK ILVSKEVRIY NDVHISLPRF SNNLRRHSFY
     IKSKLSNSTK NTCQFFTNRI ISCWNKLPPH IFPSFPNSDV FRCNISFNFV EPFLILKHSN
     F
//