ID E3N0K6_CAERE Unreviewed; 387 AA.
AC E3N0K6;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Peptidase A1 domain-containing protein {ECO:0000259|PROSITE:PS51767};
GN ORFNames=CRE_11371 {ECO:0000313|EMBL:EFP13377.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase A1 family.
CC {ECO:0000256|ARBA:ARBA00007447}.
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DR EMBL; DS268505; EFP13377.1; -; Genomic_DNA.
DR RefSeq; XP_003098083.1; XM_003098035.1.
DR AlphaFoldDB; E3N0K6; -.
DR STRING; 31234.E3N0K6; -.
DR MEROPS; A01.053; -.
DR EnsemblMetazoa; CRE11371.1; CRE11371.1; WBGene00067451.
DR eggNOG; KOG1339; Eukaryota.
DR HOGENOM; CLU_013253_3_4_1; -.
DR InParanoid; E3N0K6; -.
DR OMA; CATIRTQ; -.
DR OrthoDB; 615305at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd05471; pepsin_like; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 2.
DR InterPro; IPR001461; Aspartic_peptidase_A1.
DR InterPro; IPR034164; Pepsin-like_dom.
DR InterPro; IPR033121; PEPTIDASE_A1.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR PANTHER; PTHR47966:SF8; ASPARTIC PROTEASE 1-RELATED; 1.
DR PANTHER; PTHR47966; BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED; 1.
DR Pfam; PF00026; Asp; 1.
DR PRINTS; PR00792; PEPSIN.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR PROSITE; PS51767; PEPTIDASE_A1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..387
FT /note="Peptidase A1 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013356774"
FT DOMAIN 64..381
FT /note="Peptidase A1"
FT /evidence="ECO:0000259|PROSITE:PS51767"
FT ACT_SITE 82
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT ACT_SITE 270
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
SQ SEQUENCE 387 AA; 42457 MW; 4DA71984C5A46979 CRC64;
MNLIFLLSLI TLTSAISYSS PIQRAGSLRA KLLKNGKYPE FLAAQKKLRA ATSQPFLDYS
DDYYRVKMEL GTPPQAFTVS LDTASSFLWV LDVNCKSKDC KGDHYEKDTY NNSDSTTFQC
GAGTFVAQFD GQPVTGYLAK ETFTLANSLN IRNQDFGSAQ TVPDLYLEQP VDGVLGFGLP
AMAVNGTKTP LDTLMPLLDL KLFTIWMDKI TPKSMAGNAG LITYGALDSV NCDSKINYVP
LNVMGYWGFA LDGFAIGTFT RQRKEQVISD TASGWIGAPP TVISTIVKAT GAKFDWNLEL
YTVPCSQMTT QPDLIFTING INYPVKSVEY ILDLGLDSRQ CALTFFGMSA SSFGPAWVLG
DTFIRSYCHV YDYGNMRIGL AKAHSSV
//
