ID E3N907_CAERE Unreviewed; 319 AA.
AC E3N907;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=EGF-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CRE_21495 {ECO:0000313|EMBL:EFO90065.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; DS268560; EFO90065.1; -; Genomic_DNA.
DR RefSeq; XP_003095156.1; XM_003095108.1.
DR AlphaFoldDB; E3N907; -.
DR STRING; 31234.E3N907; -.
DR EnsemblMetazoa; CRE21495.1; CRE21495.1; WBGene00069116.
DR GeneID; 9807143; -.
DR KEGG; crq:GCK72_015695; -.
DR CTD; 9807143; -.
DR eggNOG; KOG1218; Eukaryota.
DR HOGENOM; CLU_1023915_0_0_1; -.
DR InParanoid; E3N907; -.
DR OMA; ACENDAP; -.
DR OrthoDB; 2878505at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005112; F:Notch binding; IEA:InterPro.
DR GO; GO:0001708; P:cell fate specification; IEA:InterPro.
DR GO; GO:0007219; P:Notch signaling pathway; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR001774; DSL.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR039178; Lag2.
DR PANTHER; PTHR22669:SF15; DELTA-LIKE PROTEIN; 1.
DR PANTHER; PTHR22669; DELTA/SERRATE/LAG-2 DOMAIN PROTEIN; 1.
DR SMART; SM00051; DSL; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR PROSITE; PS51051; DSL; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..319
FT /note="EGF-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003176155"
FT DOMAIN 117..158
FT /note="DSL"
FT /evidence="ECO:0000259|PROSITE:PS51051"
FT DOMAIN 161..203
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 119..128
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00377"
FT DISULFID 149..158
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00377"
FT DISULFID 193..202
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 319 AA; 37133 MW; BAC7A81EC08D7315 CRC64;
MRLLLLYFSF LLLSSSAASS LTTGPGILEI LIESGVSTDV GFVVNCDENN HVTWRHLKPN
TPELLIFDEF NQTNPYYPIN VAVHGNVTSH IMIMYPNQGL YDIDYLPLPY TGLQMKYKCA
ENRYGNKCEQ HCSEYRDNWR CDQFGHHSCA DGYCGWNCHK SVSECNNYCK CQNGGKCYPH
PFLSPDYLIM CECPPGYHGD YCEEFKYFDR KLEFSTNFGL NTTVKNKFSN RTDIYQLFEK
YEKEQRTSGN KEILSFFVPF KIPAKQWILI WLVVMSGYCI YKFCVESENE EKTPKTSKVE
KKKTSEEEKK CILIEMNDM
//
