ID E3NUM6_CAERE Unreviewed; 762 AA.
AC E3NUM6;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=ABC transmembrane type-1 domain-containing protein {ECO:0000259|PROSITE:PS50928};
GN ORFNames=CRE_07965 {ECO:0000313|EMBL:EFO95987.1};
OS Caenorhabditis remanei (Caenorhabditis vulgaris).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=31234 {ECO:0000313|Proteomes:UP000008281};
RN [1] {ECO:0000313|Proteomes:UP000008281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB4641 {ECO:0000313|Proteomes:UP000008281};
RG Caenorhabditis remanei Sequencing Consortium;
RA Wilson R.K.;
RT "PCAP assembly of the Caenorhabditis remanei genome.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
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DR EMBL; DS270607; EFO95987.1; -; Genomic_DNA.
DR RefSeq; XP_003087895.1; XM_003087847.1.
DR AlphaFoldDB; E3NUM6; -.
DR STRING; 31234.E3NUM6; -.
DR EnsemblMetazoa; CRE07965.1; CRE07965.1; WBGene00076072.
DR eggNOG; ENOG502TJZ8; Eukaryota.
DR HOGENOM; CLU_019602_20_0_1; -.
DR InParanoid; E3NUM6; -.
DR OrthoDB; 5466990at2759; -.
DR Proteomes; UP000008281; Unassembled WGS sequence.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0071705; P:nitrogen compound transport; IEA:InterPro.
DR CDD; cd13619; PBP2_GlnP; 1.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 4.
DR InterPro; IPR010065; AA_ABC_transptr_permease_3TM.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR NCBIfam; TIGR01726; HEQRo_perm_3TM; 1.
DR PANTHER; PTHR35936:SF19; ABC TRANSPORTER ARGININE-BINDING PROTEIN ARTJ-RELATED; 1.
DR PANTHER; PTHR35936; MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF00497; SBP_bac_3; 2.
DR SMART; SM00062; PBPb; 2.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF161098; MetI-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 2.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008281};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 570..588
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 600..623
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 734..756
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 564..753
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 762 AA; 80510 MW; C7C0B19EE12E7057 CRC64;
MCLPWTHGPQ TAEPPTKEQP SVHQSKHPFS LRLAIGAVIA GLVMLVAGSA AQAAPPSAGP
AHAAPAKTAD LKGKKFVIAT DTTFAPFEFR EGGKLVGIDM DLLNAIAEKE DFQVEIQSLG
FQAAVSAVTS GQADGVIAGM SITDERKQTF DFSDPYFDSG VQMAVAKNSD VKGYDDLKGK
TVVAKGGSEG ESEAKKLSEK YGFTVKALDQ STSLIESVKN GSAAAVFDDY PVLKYGIAQG
NGLKVVTDKI PGGQYGFAVA KGKNADLLAA FDEGLAALKS DGSYDKVLEK YLGTGGTAGS
GGEAPAAMDL GGKKFTIATD TTFAPFEFRK DGKLVGIDMD LLNRIAKEEN FQVDVQSLGF
QAAVSAVTSG QADGVIAGMS ITDERKQTFD FSDPYFDSGV QMAVAKNSDV KGYEDLKGKT
VVAKGGSEGE SEAKKLSEKY GFTVKALDQS TSLIESVKNG SAAAVFDDYP VLKYGIEQGN
GLKVVTAKIP GGQYGFAVAK GKNADLLEAF NNGLARMKAD GSYAKTLETY LGKDTSATAD
GGAKAQPGFI QLFVDSMPAL GEGLWNTLRI TMMAFIIAMV LGLIFGFMKI STSRTLRGIA
AVYVAVFRGT PVLVWAFLFY FGLPQLTGVT GNVFWAGTAT LALNSGAYLT EIVRGGLQAV
DPGQMEAARS LGLGWGKSMQ RVVVPQAVKI STPAIINQFV ITLKDSSLLL TIGFAELLYQ
AQQIYAANYR TTEMLIIVGI MYFVVITLLT CVANIVDRKV NK
//
