ID E3QA45_COLGM Unreviewed; 1035 AA.
AC E3QA45;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=Pro-apoptotic serine protease NMA111 {ECO:0000256|ARBA:ARBA00020338};
DE AltName: Full=Pro-apoptotic serine protease nma111 {ECO:0000256|ARBA:ARBA00021524};
GN ORFNames=GLRG_02877 {ECO:0000313|EMBL:EFQ27733.1};
OS Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize
OS anthracnose fungus) (Glomerella graminicola).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum graminicola species complex.
OX NCBI_TaxID=645133 {ECO:0000313|Proteomes:UP000008782};
RN [1] {ECO:0000313|Proteomes:UP000008782}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M1.001 / M2 / FGSC 10212 {ECO:0000313|Proteomes:UP000008782};
RX PubMed=22885923; DOI=10.1038/ng.2372;
RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA Ma L.-J., Vaillancourt L.J.;
RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT by genome and transcriptome analyses.";
RL Nat. Genet. 44:1060-1065(2012).
CC -!- FUNCTION: Nuclear serine protease which mediates apoptosis.
CC {ECO:0000256|ARBA:ARBA00002558}.
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
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DR EMBL; GG697338; EFQ27733.1; -; Genomic_DNA.
DR RefSeq; XP_008091753.1; XM_008093562.1.
DR AlphaFoldDB; E3QA45; -.
DR STRING; 645133.E3QA45; -.
DR MEROPS; S01.412; -.
DR EnsemblFungi; EFQ27733; EFQ27733; GLRG_02877.
DR GeneID; 24408242; -.
DR VEuPathDB; FungiDB:GLRG_02877; -.
DR eggNOG; KOG1421; Eukaryota.
DR HOGENOM; CLU_003212_0_0_1; -.
DR OrthoDB; 1779375at2759; -.
DR Proteomes; UP000008782; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.120; -; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR025926; PDZ-like_dom.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR46366; PRO-APOPTOTIC SERINE PROTEASE NMA111; 1.
DR PANTHER; PTHR46366:SF8; PRO-APOPTOTIC SERINE PROTEASE NMA111; 1.
DR Pfam; PF12812; PDZ_1; 2.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022825};
KW Protease {ECO:0000256|ARBA:ARBA00022825};
KW Reference proteome {ECO:0000313|Proteomes:UP000008782};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825}.
FT DOMAIN 406..482
FT /note="PDZ-like"
FT /evidence="ECO:0000259|Pfam:PF12812"
FT DOMAIN 881..958
FT /note="PDZ-like"
FT /evidence="ECO:0000259|Pfam:PF12812"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1035 AA; 114244 MW; 2010B549157318EC CRC64;
MNGNNTSPRT KRKAPPSPEG LRPHKQHRAL NGKLSAGDNT PEVELEHGAF VEEDESDFED
PARLNSMFPI TQEPEAWQKT IENVVSNVVS IRFCQTCSFD TDAALTSEAT GFVVDAQKGY
VLTNRHVVGA GPFWGYIVFD NHEEVDAYPV YRDPVHDFGI LRFDPKAVKY MKLNALVLRP
DLAKEWVTAN ASTVGVEIRV VGNDAGEKLS ILSGFISRLD RNAPEYGEGY SDFNTCYYQA
NAAASGGSSG SPVVNIDGFA VALQAGGRSD GASTDYFLPL DRPLRALECI RQGKPVTRGD
IQCQFLLKPF DECRRLGLTP EEEAAARQAF PKDNNMLVAE IVLPKGQSDK KIEEGDILIK
VNGERVGQFI RLDDLLDSNV GKTIHLQLQR GGEDIEVDVD VGDLHQITPD RFVSVAGASF
HSLSYQQARL YGVACEGVFV CEATGSFRFD NADNGWLIQT VDHKKTPDLE TFIEVMKAIP
DKSRVVVTYK HLRDLHTLNT TVIYVDRHWS AKMKMAVRND ETGLWDFTDL ADPLPPKAPV
ARSASFIELE NVKHKAIADL VRSFVHVNCT MPVKLDGFPK NRKWGMGLVI DAEKGLVVIS
RAIVPYDLCD VTITIADSII VEGKVVFLHP LQNYAIVQYD PKLVNAPVQS ARLSTDSITQ
GASTIFMGYN RIGKIVHATT TVTEVTAVAI PANSGAPRYR AINVDAITVD TSLSNQCGSG
VLVADDGTVQ ALWLTYLGER SACSNRDEEY HLGLATPTLL PVVSQIQQGI VPKLRMLSVE
FRAIAMAQAR VMGVSDEWIR KVTEANKTHH QLFMVSKRTF ERGEQSGALL EGDILLTLNG
KVITRVSELD VMYSHEVLDA VIVRNCEEIH IKAHTVAADD VETDHAISFC GAILHRPHHA
VRQQISKLHS EVYVSARTRG SPSYQYGLAP TNFITHVNGK PTPDLETFLA SVQGIPDNTY
FRLKAVTFDS VPWVITMKKN EHYFPTTEWI KDPAEACGWR RKTYEGGKVF EGEGPDGVLP
VSEDTEMVEE PAAPI
//
