ID E3S583_PYRTT Unreviewed; 1214 AA.
AC E3S583;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=PTT_17759 {ECO:0000313|EMBL:EFQ86962.1};
OS Pyrenophora teres f. teres (strain 0-1) (Barley net blotch fungus)
OS (Drechslera teres f. teres).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC Pyrenophora.
OX NCBI_TaxID=861557 {ECO:0000313|Proteomes:UP000001067};
RN [1] {ECO:0000313|EMBL:EFQ86962.1, ECO:0000313|Proteomes:UP000001067}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0-1 {ECO:0000313|EMBL:EFQ86962.1,
RC ECO:0000313|Proteomes:UP000001067};
RX PubMed=21067574; DOI=10.1186/gb-2010-11-11-r109;
RA Ellwood S.R., Liu Z., Syme R.A., Lai Z., Hane J.K., Keiper F., Moffat C.S.,
RA Oliver R.P., Friesen T.L.;
RT "A first genome assembly of the barley fungal pathogen Pyrenophora teres f.
RT teres.";
RL Genome Biol. 11:R109.1-R109.14(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; GL537212; EFQ86962.1; -; Genomic_DNA.
DR RefSeq; XP_003305025.1; XM_003304977.1.
DR AlphaFoldDB; E3S583; -.
DR STRING; 861557.E3S583; -.
DR EnsemblFungi; EFQ86962; EFQ86962; PTT_17759.
DR KEGG; pte:PTT_17759; -.
DR eggNOG; KOG0922; Eukaryota.
DR HOGENOM; CLU_001832_2_3_1; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000001067; Unassembled WGS sequence.
DR GO; GO:0071007; C:U2-type catalytic step 2 spliceosome; IEA:EnsemblFungi.
DR GO; GO:0071021; C:U2-type post-spliceosomal complex; IEA:EnsemblFungi.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:EnsemblFungi.
DR GO; GO:0000386; F:second spliceosomal transesterification activity; IEA:EnsemblFungi.
DR GO; GO:0000350; P:generation of catalytic spliceosome for second transesterification step; IEA:EnsemblFungi.
DR GO; GO:0000390; P:spliceosomal complex disassembly; IEA:EnsemblFungi.
DR CDD; cd21691; GH2-like_DHX8; 1.
DR CDD; cd05684; S1_DHX8_helicase; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR049588; DHX8_GH2-like.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049621; S1_DHX8_helicase.
DR InterPro; IPR003029; S1_domain.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF85; ATP-DEPENDENT RNA HELICASE DHX8; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR Pfam; PF00575; S1; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001067}.
FT DOMAIN 249..319
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 560..723
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 741..921
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 143..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1005..1025
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 222..239
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1008..1024
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1214 AA; 135792 MW; 7621323F47511B66 CRC64;
MDDLENLEFL SLVSKVTSEI QNHLGVSDKT LAEFVIDQHA KCKGVADFKS QLEAMGAEFP
QSLVESIDRL ILTLHPKYKN KGAKAAGANG QDGGDATDRK TRVFKGLAIP DKEVDYEVAD
EAPANEAPDV DALDDTFAML EGLAGKAPGK PKARSRKRSM SPYDSDDDIA RSKRYRRRNT
SGSRSRSRST SPRRGREQND ELVFEDEFGR TRTVKPSNKQ RTRKKYRDED LDEFRRPPTP
ELDEEPVLYK IYNGKVTGIK DFGCFVNIQG VKGKVDGLVH VTQMMEGRVN HPSDLVSRWQ
EVKVKVIKTE NGRISLSMKE VDQQTGRDLA PGKRIASFGT GANSSGLGGI PGVDSTVPVV
EDGYNGRKNG MRKRMTSPER WEIKQLIASG VIPKSDYPNI DEDYNAHING EGGFEEEEDV
DIEVREEEPP FLAGQTKQSL ELSPIRVVKA PDGSLNRAAM AGDTLAKERR DLKQQEAQEK
AAKEAANVDL SSQWNDPMAQ QRQFASDLRN TRTNEPAQAL PEWKKISTNS RETSFGKRTN
MSIKEQRESL PVYKFRNKLL EAIANNQILI VVGDTGSGKT TQMTQYLAEA GYGNELVIGC
TQPRRVAAMS VAKRVAEEVG CALGNEVGYT IRFEDKTSPE TRIKYMTDGI LQREILLDPM
LSKYSCIMLD EAHERTIATD VLFGLLKKTL KRRPDMKLIV TSATLDADKF SEYFYKCPIF
SIPGRTFPVE VMYSREPESD YLDAALVTVM QIHLTEPAGD ILLFLTGKEE IDSSCEIISE
RMKALGPNVP ELMILPIYGA LPSEVASRIF EPAPNGTRKV VIATNIAETS LTIDGIYYVV
DPGFVKQSSY DGKLGMDRLQ ITPISQAQAR QRSGRAGRTG PGKCFRLYTE AAFQNEMLPT
TIPEIQRQNL SNTILMLKAM GINDLLHFDF MDPPPTNTML TALEELYQLG ALDDEGLLTR
LGRQMADFPM DPSLSKSLIK SVELQCSDEI LTIVAMISAT QNVFHRPRDK QQQADQKKQK
FNDPSGDHIT LLNVYNGWKQ GGFSTPWCHE NFIMPKNMQR VRDVRNQLLQ IMARHKHQVV
SCGRNTIKVR QALCSGFFRN SARKDPAEGY KTLVEGTPVY LHPSSSLFGK PAEHVIYHSL
VETTKEYMHF CSAIEPKWLV EAAPTFFKVA PTDRLSKRKK AERIQPLHNK FAGEDDWRLS
AQRRAGRGGG GTWG
//
