ID   E3USN3_ENTFC            Unreviewed;       401 AA.
AC   E3USN3;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Peptidase M23B {ECO:0000313|EMBL:ADO66886.1};
GN   ORFNames=pLG1-0034 {ECO:0000313|EMBL:ADO66886.1};
OS   Enterococcus faecium (Streptococcus faecium).
OG   Plasmid pLG1 {ECO:0000313|EMBL:ADO66886.1}.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=1352 {ECO:0000313|EMBL:ADO66886.1};
RN   [1] {ECO:0000313|EMBL:ADO66886.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=64/3xUW2774 {ECO:0000313|EMBL:ADO66886.1};
RC   PLASMID=pLG1 {ECO:0000313|EMBL:ADO66886.1};
RX   PubMed=20951641; DOI=10.1016/j.ijmm.2010.08.015;
RA   Laverde Gomez J.A., van Schaik W., Freitas A.R., Coque T.M., Weaver K.E.,
RA   Francia M.V., Witte W., Werner G.;
RT   "A multiresistance megaplasmid pLG1 bearing a hylEfm genomic island in
RT   hospital Enterococcus faecium isolates.";
RL   Int. J. Med. Microbiol. 301:165-175(2011).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 73 family.
CC       {ECO:0000256|ARBA:ARBA00010266}.
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DR   EMBL; HM565183; ADO66886.1; -; Genomic_DNA.
DR   AlphaFoldDB; E3USN3; -.
DR   CAZy; GH73; Glycoside Hydrolase Family 73.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004040; F:amidase activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   CDD; cd12797; M23_peptidase; 1.
DR   Gene3D; 1.10.530.10; -; 1.
DR   Gene3D; 2.70.70.10; Glucose Permease (Domain IIA); 1.
DR   InterPro; IPR011055; Dup_hybrid_motif.
DR   InterPro; IPR002901; MGlyc_endo_b_GlcNAc-like_dom.
DR   InterPro; IPR016047; Peptidase_M23.
DR   PANTHER; PTHR21666:SF270; OUTER MEMBRANE ANTIGENIC LIPOPROTEIN B; 1.
DR   PANTHER; PTHR21666; PEPTIDASE-RELATED; 1.
DR   Pfam; PF01832; Glucosaminidase; 1.
DR   Pfam; PF01551; Peptidase_M23; 1.
DR   SUPFAM; SSF51261; Duplicated hybrid motif; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius}; Plasmid {ECO:0000313|EMBL:ADO66886.1};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022597}.
FT   TRANSMEM        21..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          92..225
FT                   /note="Mannosyl-glycoprotein endo-beta-N-
FT                   acetylglucosamidase-like"
FT                   /evidence="ECO:0000259|Pfam:PF01832"
FT   DOMAIN          283..362
FT                   /note="Peptidase M23"
FT                   /evidence="ECO:0000259|Pfam:PF01551"
SQ   SEQUENCE   401 AA;  43250 MW;  CEF3ED8149DE2AE9 CRC64;
     MENQNESLIK QYVKRRAKRR LFLWLFGTSA GLITILITVF VTLFLILAAG SIDNSDSDSS
     SGDEAFTGEY SEGLPIYKEI KGRGPFSDEI AQYAVGAAVK YKLLPSVILS QYGYESAFGT
     SASARNDLNY FGITWFDGCL FPKGTARGIG GIEGGWYMKF PNSKAAFSYY GFMVATQSNF
     NACVGNKSPG ASLLILGRGG YAAAGITEDS PYYTGCMSII TSNKLTEYDE FAIKHWGEGG
     NNNGTITGEW TNPFPGSSLD KNSFSGGQLF GTNPGGEFRP NGFHDGLDFG SVDHPGSEIH
     AVHGGKVVYV GNPGISGLGA CVIVINYDGL NMVYQEFANS TGNSRVKVGD QVKVGQVIGI
     RDTAHLHLGF TRMDWRQAQG HAFTDDGTWI DPLPFLNSSK K
//