ID   E4KMG4_9LACT            Unreviewed;       738 AA.
AC   E4KMG4;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=Peptidase S8/S53 domain-containing protein {ECO:0000259|Pfam:PF00082};
GN   ORFNames=HMPREF9257_0262 {ECO:0000313|EMBL:EFR31871.1};
OS   Eremococcus coleocola ACS-139-V-Col8.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Eremococcus.
OX   NCBI_TaxID=908337 {ECO:0000313|EMBL:EFR31871.1, ECO:0000313|Proteomes:UP000005990};
RN   [1] {ECO:0000313|EMBL:EFR31871.1, ECO:0000313|Proteomes:UP000005990}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ACS-139-V-Col8 {ECO:0000313|EMBL:EFR31871.1,
RC   ECO:0000313|Proteomes:UP000005990};
RA   Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA   Nelson K.E.;
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S8 family.
CC       {ECO:0000256|ARBA:ARBA00011073}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFR31871.1}.
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DR   EMBL; AENN01000005; EFR31871.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4KMG4; -.
DR   STRING; 908337.HMPREF9257_0262; -.
DR   eggNOG; COG1404; Bacteria.
DR   OrthoDB; 9798386at2; -.
DR   Proteomes; UP000005990; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd04847; Peptidases_S8_Subtilisin_like_2; 1.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR034074; Y4bN_pept_dom.
DR   PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR   PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005990}.
FT   DOMAIN          264..559
FT                   /note="Peptidase S8/S53"
FT                   /evidence="ECO:0000259|Pfam:PF00082"
SQ   SEQUENCE   738 AA;  82132 MW;  1EED71A041FA1F13 CRC64;
     MSDKRRNHLW IPDEEVTRVD KKPTGRTTPR NISFTEHGQK LSSSLQSIKQ AIENVSEDDS
     LSDTGLMIFK VELPDGEKIK DKKDLFTSTG MEVKVVKSEN KAVIATTENQ FQSLKKRIDD
     YTRSGSGKTY FDYIEDFKPY LGSEKNSSSL KKTTCSDLVS DSLDIQLMLV PNLREEIYDL
     AIQRLVEKIG DRDGIIQEEL YYLSDNTPVI RVIIPSNSLF HYENDSAIYR IEETDFFSAD
     VASKDAIDLN ELELDDSVLI DKLPIVTVLD SGVNFPEGLE PLILHHWTDG SSGGDSEHGT
     KVASRVAFKY ICDQLPSTKI TPRTRIIDCN ILDGSVPVNV FIKRIQNAVA TFCDISKIYN
     LSANASSPIE GDEMSILGYE LDALQLKRNV QFVISAGNHQ LWSTESCLED ILDDDDSRVS
     APADSMLSVV VGATSGETHP NSLSAINEVS SYSRIGSGFN GFSKPDLTAY GGCITCIAGS
     VSVPEDKYSL LLDKNGQLTP DAGTSFTAPV VAGDFAEILG IIPNQDILLA KVLLYHNAMP
     IWDEDSITDE ELAYTHNLYG RGLSNVDESK YSSPSKVTFV RTGTLNKVTK ERVTIYMPEI
     LAAQVGRNVA KVSVTCISMP PVDRTKGTEY LGAYIRASLK KSSSDGRLKP VKQDFKVGRQ
     KWDVCHQFTK LFSKFEAGDW QIWLELFSRW DEENIDVPYA LAVTIEDVSN TLDVYSEIEA
     LNRYRAINTL RLRLDSQS
//