ID E4LAD0_9FIRM Unreviewed; 727 AA.
AC E4LAD0;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Orn/Lys/Arg decarboxylase, major domain protein {ECO:0000313|EMBL:EFR42257.1};
GN ORFNames=HMPREF9220_0517 {ECO:0000313|EMBL:EFR42257.1};
OS Dialister micraerophilus UPII 345-E.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Dialister.
OX NCBI_TaxID=910314 {ECO:0000313|EMBL:EFR42257.1, ECO:0000313|Proteomes:UP000004594};
RN [1] {ECO:0000313|EMBL:EFR42257.1, ECO:0000313|Proteomes:UP000004594}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UPII 345-E {ECO:0000313|EMBL:EFR42257.1,
RC ECO:0000313|Proteomes:UP000004594};
RA Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC {ECO:0000256|ARBA:ARBA00010671}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFR42257.1}.
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DR EMBL; AENT01000029; EFR42257.1; -; Genomic_DNA.
DR RefSeq; WP_007555172.1; NZ_AENT01000029.1.
DR AlphaFoldDB; E4LAD0; -.
DR eggNOG; COG1982; Bacteria.
DR OrthoDB; 9815233at2; -.
DR Proteomes; UP000004594; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016831; F:carboxy-lyase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR CDD; cd00615; Orn_deC_like; 1.
DR Gene3D; 3.40.50.220; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR005308; OKR_de-COase_N.
DR InterPro; IPR011193; Orn/lys/arg_de-COase.
DR InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR InterPro; IPR027464; Ornithine_deCO2ase_N.
DR InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR45229:SF3; BIODEGRADATIVE ARGININE DECARBOXYLASE; 1.
DR PANTHER; PTHR45229; CONSTITUTIVE ORNITHINE DECARBOXYLASE; 1.
DR Pfam; PF01276; OKR_DC_1; 1.
DR Pfam; PF03711; OKR_DC_1_C; 1.
DR Pfam; PF03709; OKR_DC_1_N; 1.
DR PIRSF; PIRSF009393; Orn_decarb; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR009393-1}.
FT DOMAIN 18..102
FT /note="Orn/Lys/Arg decarboxylase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03709"
FT DOMAIN 108..550
FT /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT attachment site"
FT /evidence="ECO:0000259|Pfam:PF01276"
FT DOMAIN 575..704
FT /note="Orn/Lys/Arg decarboxylase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03711"
FT MOD_RES 354
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR009393-1"
SQ SEQUENCE 727 AA; 81831 MW; 382B3A47C12B7BB1 CRC64;
MKKLKLSYSD KARELFEIRT AREIVDLAKT DFLDIATIVI TADDEALLKP AVAEFKIPVF
LIAEAGKPIS DELLSKVFRV IDLDKSGVQF YNDQIENAAT TYENKLLPPF FKALVDFVEA
GFGNYATPGH HGGQYFCKHP SGKAFVDFFG ENLFRADLSS SDVQMGDLLI HEGAPCDAEQ
YAASVFKADK TYFVLNGTSG SNKVVLNAAL APGDIILYDR NNHKSISQGA LVQAGAIPVF
LEDARNPYGS IGGIKSHCFE EDYIRKLIAE KDPVKAKEER PIRIAVIQLG TYDGCIYNAR
QVVDRIGHLC DYILFDSAWV GYEQFIPMMK DCSPMLLELG PNDPGIFVTQ SVHKQLAGIS
MASQIHKKDR HIKGQDRYIP HKRVNNAFML HASTSPCYPI FASLDVNAKM HEGKAGIRMW
VDTVKNAIEA RKAVLRNCKY VRPLLPKEVY GKKWEDGDTE KMANDLEYWK LTPGAKWHGF
KGYGKDQYFV DPMKLQFLTA GINIETGEYE ENGVPANVIA NYLRENGIIP EKTDLNAVLF
VLTPAETKSK MDDLIAKLVR FEQLYEADAP MEELLPNIYA ANKDVYKGFT IKMLCQKMHN
FYKDRKVNVL QERLFHADYL PEWAMTAQQA NFEFVANHGE LIPLDQAQGR IALEGALPYP
PGILTIHPGE RWSETCVNYF LALQEGINLL PGFTPEIQGV YLETEPDGSK RAYGYVLKKE
YDPKFQK
//
