ID E4LBY1_9FIRM Unreviewed; 501 AA.
AC E4LBY1;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Succinate CoA transferase {ECO:0000313|EMBL:EFR60698.1};
DE EC=2.8.3.- {ECO:0000313|EMBL:EFR60698.1};
GN ORFNames=HMPREF9199_1293 {ECO:0000313|EMBL:EFR60698.1};
OS Veillonella sp. oral taxon 158 str. F0412.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Veillonella.
OX NCBI_TaxID=879309 {ECO:0000313|EMBL:EFR60698.1, ECO:0000313|Proteomes:UP000003565};
RN [1] {ECO:0000313|EMBL:EFR60698.1, ECO:0000313|Proteomes:UP000003565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0412 {ECO:0000313|EMBL:EFR60698.1,
RC ECO:0000313|Proteomes:UP000003565};
RA Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFR60698.1}.
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DR EMBL; AENU01000007; EFR60698.1; -; Genomic_DNA.
DR RefSeq; WP_009351031.1; NZ_AENU01000007.1.
DR AlphaFoldDB; E4LBY1; -.
DR STRING; 879309.HMPREF9199_1293; -.
DR eggNOG; COG0427; Bacteria.
DR OrthoDB; 9801795at2; -.
DR Proteomes; UP000003565; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Transferase {ECO:0000313|EMBL:EFR60698.1}.
FT DOMAIN 17..219
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 320..466
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 291
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 266..270
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 361
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 381
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 385
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 405
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 501 AA; 54574 MW; 51D249C6D8A98F92 CRC64;
MVIDIKDRVK SAALQGKIVT ASEAALLINP NDKVGISGFT PSGYVKAVPL ALAERMEKEP
FKIDLWTGAS VGDEADGALT RVNGIHRRFP YQTNNDTRKA LNGGKINYID MHLSTMAQNV
RYGFFGDLDV AIIEAAQINE DGSIVPTTSV GNSPTFVSQA KKVIVEVNVS QPLSLVGMHD
IYEPLDPPYR KPIPLETPGD RIGTDAIPCD PEKIVAIVPC DIPDTTRPLA PIDDDAKAMS
QHLIDFFQEE IKGGRLPENL LPLQSGVGSV ANAVISGLAK GPFTNLSIFT EVIQDGMFDL
IDADKVTVCS GTALSPSPEG LKRFYNNIDE YRKKIILRPQ EISNNPGIAR RLGVIAMNTA
IEFDIFGNVN STHIMGSKMM NGVGGSGDFA RSAYLTIFCT NSVAKNGDIS SIVPYVSHVD
HTEHDTMIFC TEQGVADCRG LSPVERARLI IEKCAHPDYK PMLTEYLEKA LEATKNAHTP
MLLDEALSWH KRFTETGSMK K
//
