ID E4N1N4_KITSK Unreviewed; 550 AA.
AC E4N1N4;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Putative L-aspartate-beta-decarboxylase {ECO:0000313|EMBL:BAJ32068.1};
DE EC=4.1.1.12 {ECO:0000313|EMBL:BAJ32068.1};
GN OrderedLocusNames=KSE_63100 {ECO:0000313|EMBL:BAJ32068.1};
OS Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304
OS / NBRC 14216 / KM-6054) (Streptomyces setae).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=452652 {ECO:0000313|EMBL:BAJ32068.1, ECO:0000313|Proteomes:UP000007076};
RN [1] {ECO:0000313|EMBL:BAJ32068.1, ECO:0000313|Proteomes:UP000007076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 /
RC KM-6054 {ECO:0000313|Proteomes:UP000007076};
RX PubMed=21059706; DOI=10.1093/dnares/dsq026;
RA Ichikawa N., Oguchi A., Ikeda H., Ishikawa J., Kitani S., Watanabe Y.,
RA Nakamura S., Katano Y., Kishi E., Sasagawa M., Ankai A., Fukui S.,
RA Hashimoto Y., Kamata S., Otoguro M., Tanikawa S., Nihira T., Horinouchi S.,
RA Ohnishi Y., Hayakawa M., Kuzuyama T., Arisawa A., Nomoto F., Miura H.,
RA Takahashi Y., Fujita N.;
RT "Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
RT snapshot of the family Streptomycetaceae.";
RL DNA Res. 17:393-406(2010).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; AP010968; BAJ32068.1; -; Genomic_DNA.
DR RefSeq; WP_014139364.1; NC_016109.1.
DR AlphaFoldDB; E4N1N4; -.
DR STRING; 452652.KSE_63100; -.
DR KEGG; ksk:KSE_63100; -.
DR PATRIC; fig|452652.3.peg.6329; -.
DR eggNOG; COG0436; Bacteria.
DR HOGENOM; CLU_038911_0_0_11; -.
DR Proteomes; UP000007076; Chromosome.
DR GO; GO:0047688; F:aspartate 4-decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.20.110; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR022518; Aspartate_4-decarboxylase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR03801; asp_4_decarbox; 1.
DR PANTHER; PTHR43795:SF10; AMINOTRAN_1_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43795; BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:BAJ32068.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000007076}.
FT DOMAIN 186..523
FT /note="Aminotransferase class I/classII"
FT /evidence="ECO:0000259|Pfam:PF00155"
SQ SEQUENCE 550 AA; 60690 MW; C4210B139779B818 CRC64;
MSKPSISREE IKRLSRLSPF ELKGEFIKLA EQYQADQPGQ KGKTTAHMLN AGRGNPNWVC
TGPREAMLAL GHFALSESRR VWTADNLGGM PEQDGISGRY DHFARSHPEL PGIDLLTACV
SLAVDRFDLD RDAFLHELAD ASIGDNYPVP DRMLTGAEQI VTGYLHDELM DRRPPEGDLD
LFATEGGTAA MCYIFDSLMK NGILHKGDKI ALMVPVFTPY IEIPELDTYE FDVVTVEASS
FAEAGVREWR YPTEEVAKLA DPAVKLVCLV NPSNPPSLAL SQRVTDQIKS IVATDNPNLI
IVTDDVYGTF VNHFRSIAAD LPRNTLLVYS YSKHYGCTGH RLGVIGLQRD NVIDDALAAL
PQADKDRLAK RYGSLSLDPG SIRFIDRLVA DSRQVALNHT AGLSLPQQAQ LTLFSLFALL
PEGKAYKAKV QAIVQQRLAL LLEGSGMKIS DDPQRAGYYI ELDLLAEAER TSGPEFAAFL
QKNYEPTEPL FRLAEQTGVV LLNGGGFDGP QWSVRVSLAN LDDLDYLKIG HHLKAIFDDY
RAEWQAAGGK
//
