ID E4N469_KITSK Unreviewed; 1975 AA.
AC E4N469;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:BAJ26000.1};
GN OrderedLocusNames=KSE_01490 {ECO:0000313|EMBL:BAJ26000.1};
OS Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304
OS / NBRC 14216 / KM-6054) (Streptomyces setae).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=452652 {ECO:0000313|EMBL:BAJ26000.1, ECO:0000313|Proteomes:UP000007076};
RN [1] {ECO:0000313|EMBL:BAJ26000.1, ECO:0000313|Proteomes:UP000007076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 /
RC KM-6054 {ECO:0000313|Proteomes:UP000007076};
RX PubMed=21059706; DOI=10.1093/dnares/dsq026;
RA Ichikawa N., Oguchi A., Ikeda H., Ishikawa J., Kitani S., Watanabe Y.,
RA Nakamura S., Katano Y., Kishi E., Sasagawa M., Ankai A., Fukui S.,
RA Hashimoto Y., Kamata S., Otoguro M., Tanikawa S., Nihira T., Horinouchi S.,
RA Ohnishi Y., Hayakawa M., Kuzuyama T., Arisawa A., Nomoto F., Miura H.,
RA Takahashi Y., Fujita N.;
RT "Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
RT snapshot of the family Streptomycetaceae.";
RL DNA Res. 17:393-406(2010).
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DR EMBL; AP010968; BAJ26000.1; -; Genomic_DNA.
DR RefSeq; WP_014133321.1; NC_016109.1.
DR STRING; 452652.KSE_01490; -.
DR KEGG; ksk:KSE_01490; -.
DR PATRIC; fig|452652.3.peg.140; -.
DR eggNOG; COG1357; Bacteria.
DR eggNOG; COG1409; Bacteria.
DR eggNOG; COG2319; Bacteria.
DR eggNOG; COG4916; Bacteria.
DR eggNOG; COG5635; Bacteria.
DR HOGENOM; CLU_002061_0_0_11; -.
DR Proteomes; UP000007076; Chromosome.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00200; WD40; 2.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 2.160.20.80; E3 ubiquitin-protein ligase SopA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR001646; 5peptide_repeat.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22847:SF637; WD REPEAT DOMAIN 5; 1.
DR PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF00805; Pentapeptide; 2.
DR Pfam; PF13676; TIR_2; 1.
DR Pfam; PF00400; WD40; 15.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00255; TIR; 1.
DR SMART; SM00320; WD40; 15.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF141571; Pentapeptide repeat-like; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS50837; NACHT; 1.
DR PROSITE; PS50104; TIR; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 3.
DR PROSITE; PS50082; WD_REPEATS_2; 12.
DR PROSITE; PS50294; WD_REPEATS_REGION; 9.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007076};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 12..145
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT DOMAIN 720..838
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REPEAT 1303..1342
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1343..1384
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1385..1426
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1475..1516
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1517..1558
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1597..1620
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1621..1662
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1663..1704
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1705..1746
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1747..1788
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1832..1873
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1874..1907
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 149..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1087..1106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1975 AA; 212000 MW; 573F5F85B7496A4F CRC64;
MGALDATPGG PGPIDFFISY SPADERWAAW IAWTLEEAGY RAFLQAWDFV PGTNFVDFMD
RGITESAAVI ALLSRNYERS RYGRMEWQAA LRADPDAPER RLVTVRIEDI PVDGLLATLT
YIDLVGVARP AEARQLLLTR VAAAMDGRSR PELRPGYPGG VPGPADVPGA PGTLSPAGRT
PAGAPTATTA ATAAARGGRR RRPSTQPAYP LAAGRAGGRE AVTVLHLAGP GFGRGADPAE
LQAAVWGDLV ELADSGAPAP ELVVVTGDLT ASGSPRECEQ ALSFLTGMRT LLGLEPHRVA
IVPGGQDVSQ AASRAYFATC EADEVRPAPP YWPKWRHYSR LFQEFYQGLD LVFDSAQPWT
LFPVPELGTV VAGLNSTMAW SHRPDDRHGW LGPEQTAWFA QALRPYENDG WLRIGALRHP
AAAARPARGG PADEPLRDAD RFTRLTAPRL HLLLHGPTAA RTALGALTTS AGELTTLAAP
AAGGHQLLQL TREGLTRWSA PGAEPLRTAA PWPRAGRVFP APEPAAQPPT AEPPELDGAR
PATAPEREVR RPASPLETLL ARVAEVCRTR HQGAQIREVA GPPPQLFVTW AESGLIRQQR
VAVSVRTPTE EDVDRFVDEV HADGAAPDAE LVHDGPPPSL ALRERARRRG VRLRSFPEFQ
GLLDLRDYVS AQSERLAADS QYQPGLYLPQ RYRDAERPGA EERDGLVDEL LRLLDSDHGR
FVLLLGDFGR GKTFALRETA RRIPAELPYL TPLFIDLSAL DKAHSLDGLV AAHLTGHGID
SLDLRTFRYM LRQGRIVLLF DGFDELVNRV SYERAADHLQ VLLDAAVDNA KIVVTSRTQH
FRSHEQVLTA LGERVGLLPR RRLVAVQDFT PHQIRSYLAN RYGDPDAAAR RMRLLEAVPD
LLALCRNPRL LSFVADLDHD RLRAVAGAGR ALSAAGLYQE LFTSWLRFEE RRGDGGPGAA
PGLRLEQLWQ AVTLLAVRLW ESGRSSIALD EIVDIAGVLT GLADSPMPTP QVAHAVGSGS
LLVRSDEGVF HFIHGSVVEW LVARAAAAAL ERGETDLLAR APLSRLAVEF LCDLADRQAV
QNWAHSVLDG PRDGGPDGTR DGARDGGEAA RLNAVKVLDR LRVPAHTVLR GAPLAGEDLS
HRDLSGVDLS GADLTDARLL GTDLSGADLR GATLAGARLD GADLSGADLR SADLRGARLL
GTDLRGARLQ GSRWQRAALI SATADPDALA APELRAAAIA PGLPVEAGFS PSEVGVPYGF
DVRSTRLPEP VAFSPDGRLL AVGSEDGSVL VCDALTGTAL RTLKDHIGRV YAVKFAGEVL
ATGSADGTVR LWDQVSGECR HRLDVHPGGV WPVSLGPGGR LVATGDPNGT VTLWDTATGR
PLHRLRGHDA PVYTAVFSPD GTLIVTGDSG GGARLWSTAT GRRRAVLPGH LGTVYRTAFS
PDGTLVATAD GGDDHGTGGT VRIWDTTGRR PLHTLTGHAG RIYTLAFHPD GDLLASGDTE
GQVRLWNPLD GTALERPDDS TGKIYQVAFD EAGTRLAASD SDGGVRIWRV TRHSPDQRGG
RHRVVPLRRQ PPEHRGSVWA CRFRPGAGRG GAETDALLVT GGNDGLVRLW DPASGRSRQL
LRGHGRRIGS LSFSGDGTLL AAGGNDGVVR LWEPATGRRV RELTGRSSRL VSAEFSPEDA
VLATATNDGD LCLWNARTGE YLREMDVETE HVWAEGFSAD GALVATANDD DTVRIWYRRT
GAHLTTLREH RGRVRSIAFT PDGRRLLTGC DDHKVRISDL DTGRVEAELV GHTDRVYAVT
AVTGTPDGDW LASASWDGTA LVWRDGAVRH RLTGHVGRLW TAAAHPARPL LATAGDDRVV
RLWDTRTGAP LAGLRGHTGR ILAVTFNPDG TLLASGGEDG TVRLWRIGPE GRPAPLATLL
GAPAGWAALL PSGAYKYEGD VAGEFWHAVG MCRFEPGELD AHLPGVHRLP PEAEL
//
