ID E4N629_KITSK Unreviewed; 224 AA.
AC E4N629;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Putative TetR family transcriptional regulator {ECO:0000313|EMBL:BAJ26660.1};
GN OrderedLocusNames=KSE_08210 {ECO:0000313|EMBL:BAJ26660.1};
OS Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304
OS / NBRC 14216 / KM-6054) (Streptomyces setae).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=452652 {ECO:0000313|EMBL:BAJ26660.1, ECO:0000313|Proteomes:UP000007076};
RN [1] {ECO:0000313|EMBL:BAJ26660.1, ECO:0000313|Proteomes:UP000007076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 /
RC KM-6054 {ECO:0000313|Proteomes:UP000007076};
RX PubMed=21059706; DOI=10.1093/dnares/dsq026;
RA Ichikawa N., Oguchi A., Ikeda H., Ishikawa J., Kitani S., Watanabe Y.,
RA Nakamura S., Katano Y., Kishi E., Sasagawa M., Ankai A., Fukui S.,
RA Hashimoto Y., Kamata S., Otoguro M., Tanikawa S., Nihira T., Horinouchi S.,
RA Ohnishi Y., Hayakawa M., Kuzuyama T., Arisawa A., Nomoto F., Miura H.,
RA Takahashi Y., Fujita N.;
RT "Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
RT snapshot of the family Streptomycetaceae.";
RL DNA Res. 17:393-406(2010).
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DR EMBL; AP010968; BAJ26660.1; -; Genomic_DNA.
DR RefSeq; WP_014133979.1; NC_016109.1.
DR AlphaFoldDB; E4N629; -.
DR STRING; 452652.KSE_08210; -.
DR KEGG; ksk:KSE_08210; -.
DR PATRIC; fig|452652.3.peg.810; -.
DR eggNOG; COG1309; Bacteria.
DR HOGENOM; CLU_069356_46_2_11; -.
DR Proteomes; UP000007076; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR041674; TetR_C_22.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF226; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RV1474C; 1.
DR Pfam; PF17928; TetR_C_22; 1.
DR Pfam; PF00440; TetR_N; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000007076};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 30..90
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 53..72
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 224 AA; 23389 MW; D07E346AAD883CA2 CRC64;
MTPQRAASAA HASRAPAAGA RRRPVQQRSQ ERYERLLDAC AGLLDEAGPA GLTTKEVALR
AEVPIGTLYQ FFDGREGLLA ALAARNLARF LDGLADRVAA APGPIAVAAF TEHAVDEFVA
MKRTVPGFGH LDFGLVDAVP AEVDDAHLLD AELDNNAAVA ARLRAIGGEL FAAPGYALAL
RVAMECADAV LKLAFRADPA GDPALVAECK RLLRSYLAAA PPAG
//
