ID E4NIK0_KITSK Unreviewed; 355 AA.
AC E4NIK0;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Putative esterase {ECO:0000313|EMBL:BAJ32798.1};
GN OrderedLocusNames=KSE_70400 {ECO:0000313|EMBL:BAJ32798.1};
OS Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304
OS / NBRC 14216 / KM-6054) (Streptomyces setae).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=452652 {ECO:0000313|EMBL:BAJ32798.1, ECO:0000313|Proteomes:UP000007076};
RN [1] {ECO:0000313|EMBL:BAJ32798.1, ECO:0000313|Proteomes:UP000007076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 /
RC KM-6054 {ECO:0000313|Proteomes:UP000007076};
RX PubMed=21059706; DOI=10.1093/dnares/dsq026;
RA Ichikawa N., Oguchi A., Ikeda H., Ishikawa J., Kitani S., Watanabe Y.,
RA Nakamura S., Katano Y., Kishi E., Sasagawa M., Ankai A., Fukui S.,
RA Hashimoto Y., Kamata S., Otoguro M., Tanikawa S., Nihira T., Horinouchi S.,
RA Ohnishi Y., Hayakawa M., Kuzuyama T., Arisawa A., Nomoto F., Miura H.,
RA Takahashi Y., Fujita N.;
RT "Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
RT snapshot of the family Streptomycetaceae.";
RL DNA Res. 17:393-406(2010).
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DR EMBL; AP010968; BAJ32798.1; -; Genomic_DNA.
DR RefSeq; WP_014140089.1; NC_016109.1.
DR AlphaFoldDB; E4NIK0; -.
DR STRING; 452652.KSE_70400; -.
DR KEGG; ksk:KSE_70400; -.
DR PATRIC; fig|452652.3.peg.7074; -.
DR eggNOG; COG2755; Bacteria.
DR HOGENOM; CLU_038449_4_1_11; -.
DR Proteomes; UP000007076; Chromosome.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR CDD; cd01823; SEST_like; 1.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR037460; SEST-like.
DR InterPro; IPR013830; SGNH_hydro.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR PANTHER; PTHR37981; LIPASE 2; 1.
DR PANTHER; PTHR37981:SF1; SGNH_HYDRO DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13472; Lipase_GDSL_2; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR637460-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000007076};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..355
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003184575"
FT DOMAIN 58..335
FT /note="SGNH hydrolase-type esterase"
FT /evidence="ECO:0000259|Pfam:PF13472"
FT ACT_SITE 62
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT ACT_SITE 329
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT DISULFID 81..111
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
FT DISULFID 163..187
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
FT DISULFID 243..301
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
SQ SEQUENCE 355 AA; 36923 MW; 0DFF5EF0ED247B40 CRC64;
MPTATRKTTT AALRRAVVAA VTAVVLGSCP ALAAPAAGAG PNRAPAGPGP AEPVPTVFFG
DSLAAGFGIA PVSPDGDGPF CFRAVANYPA VATRLLAERG VPLDVRADVS CSGAAVHDFW
TPQPLAADRR AAPQQDALAP DTRLLVGSVG GNTLSFGRVL KQCSATLRAG SLMPGDPVDP
DQPAADCREF FEEGAGREWL EGRFVQVEAE LTELLVRARL AAPGVRTVLV GYSRMVPADP
AACLTPAPGQ DALPFADIPP DALPFIDRVQ RRLDDLTRRV AEAGGAAYVD LYDRTGDSTA
CAGPDRGVGG LLEDSELGPD GRRIPWYVHP NERGRDLQAE QVAAAVEPLL GRAAR
//
