ID E4NPR2_HALBP Unreviewed; 466 AA.
AC E4NPR2;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Uncharacterized conserved protein {ECO:0000313|EMBL:ADQ66545.1};
GN OrderedLocusNames=Hbor_09510 {ECO:0000313|EMBL:ADQ66545.1};
GN ORFNames=C499_02272 {ECO:0000313|EMBL:ELY31020.1};
OS Halogeometricum borinquense (strain ATCC 700274 / DSM 11551 / JCM 10706 /
OS KCTC 4070 / PR3).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Halogeometricum.
OX NCBI_TaxID=469382 {ECO:0000313|EMBL:ADQ66545.1, ECO:0000313|Proteomes:UP000006663};
RN [1] {ECO:0000313|EMBL:ADQ66545.1, ECO:0000313|Proteomes:UP000006663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700274 / DSM 11551 / JCM 10706 / KCTC 4070 / PR3
RC {ECO:0000313|Proteomes:UP000006663}, and PR 3
RC {ECO:0000313|EMBL:ADQ66545.1};
RX PubMed=21304651; DOI=10.4056/sigs.23264;
RA Malfatti S., Tindall B.J., Schneider S., Fahnrich R., Lapidus A.,
RA Labuttii K., Copeland A., Glavina Del Rio T., Nolan M., Chen F., Lucas S.,
RA Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S., Anderson I.,
RA Pati A., Ivanova N., Mavromatis K., Chen A., Palaniappan K.,
RA D'haeseleer P., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Chain P.;
RT "Complete genome sequence of Halogeometricum borinquense type strain
RT (PR3).";
RL Stand. Genomic Sci. 1:150-159(2009).
RN [2] {ECO:0000313|EMBL:ELY31020.1, ECO:0000313|Proteomes:UP000011585}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11551 {ECO:0000313|EMBL:ELY31020.1,
RC ECO:0000313|Proteomes:UP000011585};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001690; ADQ66545.1; -; Genomic_DNA.
DR EMBL; AOHT01000007; ELY31020.1; -; Genomic_DNA.
DR RefSeq; WP_006053770.1; NZ_AOHT01000007.1.
DR AlphaFoldDB; E4NPR2; -.
DR STRING; 469382.Hbor_09510; -.
DR GeneID; 9992770; -.
DR KEGG; hbo:Hbor_09510; -.
DR PATRIC; fig|469382.19.peg.445; -.
DR eggNOG; arCOG00244; Archaea.
DR HOGENOM; CLU_046808_0_0_2; -.
DR OrthoDB; 194971at2157; -.
DR Proteomes; UP000006663; Chromosome.
DR Proteomes; UP000011585; Unassembled WGS sequence.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR43781; SACCHAROPINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43781:SF1; SACCHAROPINE DEHYDROGENASE; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006663}.
FT DOMAIN 8..122
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
FT REGION 358..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..402
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..430
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..466
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 466 AA; 50131 MW; 0E984AEED29668CA CRC64;
MSDDSRFLVY GAYGYTGRLI AEEAADRDLD VVLAGRDEKR TRDVANELDL PYRTFDVSQA
ATMLDDVSLV LNCAGPFDET ADHMVDACIE TETHYLDITG EIPVFERIKR RSDEADEAGI
TLLPGVGFDV VPTDCLAAHL KSRLPEATHL TLALESDGSI SPGTLKTALG DMSGGGAVRR
DGDLRWVPTG HKTRAIDFGE GLHRAVTIPW GDVSTAYVTT EIPNIEVYLS LPSKARSALT
GTSLLGGLLD TKPAQSMLQR AIERYVEGPD ERERGSSEAR IWGEARSPTD RVVSRLRTPN
TYAITVQTAL LCAKKTLNGE APTGYQTPAA AFGPDLILEI PGVERIDLKD DEIVARETGG
ESDEAADGED AEAEVALDDD AVTIDLDDDE QSSDEAEDAA DDEADTPSPR PLSDEAEPVI
RRRETEAETA EAETAEAETA EAETVEAEAT EEAEAETTEG EAAAEE
//
