ID E4NRW2_HALBP Unreviewed; 270 AA.
AC E4NRW2;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=DNA repair exonuclease {ECO:0000313|EMBL:ADQ66899.1};
GN OrderedLocusNames=Hbor_13160 {ECO:0000313|EMBL:ADQ66899.1};
GN ORFNames=C499_04033 {ECO:0000313|EMBL:ELY30406.1};
OS Halogeometricum borinquense (strain ATCC 700274 / DSM 11551 / JCM 10706 /
OS KCTC 4070 / PR3).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Halogeometricum.
OX NCBI_TaxID=469382 {ECO:0000313|EMBL:ADQ66899.1, ECO:0000313|Proteomes:UP000006663};
RN [1] {ECO:0000313|EMBL:ADQ66899.1, ECO:0000313|Proteomes:UP000006663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700274 / DSM 11551 / JCM 10706 / KCTC 4070 / PR3
RC {ECO:0000313|Proteomes:UP000006663}, and PR 3
RC {ECO:0000313|EMBL:ADQ66899.1};
RX PubMed=21304651; DOI=10.4056/sigs.23264;
RA Malfatti S., Tindall B.J., Schneider S., Fahnrich R., Lapidus A.,
RA Labuttii K., Copeland A., Glavina Del Rio T., Nolan M., Chen F., Lucas S.,
RA Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S., Anderson I.,
RA Pati A., Ivanova N., Mavromatis K., Chen A., Palaniappan K.,
RA D'haeseleer P., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Chain P.;
RT "Complete genome sequence of Halogeometricum borinquense type strain
RT (PR3).";
RL Stand. Genomic Sci. 1:150-159(2009).
RN [2] {ECO:0000313|EMBL:ELY30406.1, ECO:0000313|Proteomes:UP000011585}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11551 {ECO:0000313|EMBL:ELY30406.1,
RC ECO:0000313|Proteomes:UP000011585};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
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DR EMBL; CP001690; ADQ66899.1; -; Genomic_DNA.
DR EMBL; AOHT01000010; ELY30406.1; -; Genomic_DNA.
DR AlphaFoldDB; E4NRW2; -.
DR STRING; 469382.Hbor_13160; -.
DR KEGG; hbo:Hbor_13160; -.
DR PATRIC; fig|469382.19.peg.798; -.
DR eggNOG; arCOG00397; Archaea.
DR HOGENOM; CLU_1028978_0_0_2; -.
DR OrthoDB; 11638at2157; -.
DR Proteomes; UP000006663; Chromosome.
DR Proteomes; UP000011585; Unassembled WGS sequence.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR30337; COMPONENT OF ATP-DEPENDENT DSDNA EXONUCLEASE; 1.
DR PANTHER; PTHR30337:SF0; NUCLEASE SBCCD SUBUNIT D; 1.
DR Pfam; PF00149; Metallophos; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000313|EMBL:ADQ66899.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839, ECO:0000313|EMBL:ADQ66899.1};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000313|EMBL:ADQ66899.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006663}.
FT DOMAIN 2..214
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
SQ SEQUENCE 270 AA; 29410 MW; 7E8D205E8535376D CRC64;
MLFVSDTHLG YENRAETGSG KTVPWIDEID SRDTIRRIRT IAMERDVDAV IHTGDVLDHE
VDAVTLDAAE SSLRDLALSD IPVYCILGTH DHNAAIPYYS NSVDGIAWLK DQVRNEYLIE
LSASPTSVAG GPLDAYGVSA ENVGLDDVGK YESLGWRPSE IAFGAASPGP NVLCLHDGVT
PYRNRSTADV NLDELLAQSR VSFDCVLVGD EHRPKYDDFE NGYSFETEDG TPVLYTGPAV
RVGPAYRDHE AFVTELSISA AGVTPTRHPL
//
