ID E4Q894_CALH1 Unreviewed; 233 AA.
AC E4Q894;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=TVP38/TMEM64 family membrane protein {ECO:0000256|RuleBase:RU366058};
GN OrderedLocusNames=Calhy_2236 {ECO:0000313|EMBL:ADQ07941.1};
OS Caldicellulosiruptor hydrothermalis (strain DSM 18901 / VKM B-2411 / 108).
OC Bacteria; Bacillota; Clostridia; Caldicellulosiruptorales;
OC Caldicellulosiruptoraceae; Caldicellulosiruptor.
OX NCBI_TaxID=632292 {ECO:0000313|EMBL:ADQ07941.1, ECO:0000313|Proteomes:UP000006890};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=108;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N.,
RA Mikhailova N., Blumer-Schuette S.E., Kelly R.M., Woyke T.;
RT "Complete sequence of Caldicellulosiruptor hydrothermalis 108.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADQ07941.1, ECO:0000313|Proteomes:UP000006890}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18901 / VKM B-2411 / 108
RC {ECO:0000313|Proteomes:UP000006890};
RX PubMed=21216991; DOI=10.1128/JB.01515-10;
RA Blumer-Schuette S.E., Ozdemir I., Mistry D., Lucas S., Lapidus A.,
RA Cheng J.F., Goodwin L.A., Pitluck S., Land M.L., Hauser L.J., Woyke T.,
RA Mikhailova N., Pati A., Kyrpides N.C., Ivanova N., Detter J.C.,
RA Walston-Davenport K., Han S., Adams M.W., Kelly R.M.;
RT "Complete genome sequences for the anaerobic, extremely thermophilic plant
RT biomass-degrading bacteria Caldicellulosiruptor hydrothermalis,
RT Caldicellulosiruptor kristjanssonii, Caldicellulosiruptor kronotskyensis,
RT Caldicellulosiruptor owensenis, and Caldicellulosiruptor lactoaceticus.";
RL J. Bacteriol. 193:1483-1484(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU366058};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU366058}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TVP38/TMEM64 family.
CC {ECO:0000256|ARBA:ARBA00008640, ECO:0000256|RuleBase:RU366058}.
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DR EMBL; CP002219; ADQ07941.1; -; Genomic_DNA.
DR RefSeq; WP_013404084.1; NC_014652.1.
DR AlphaFoldDB; E4Q894; -.
DR STRING; 632292.Calhy_2236; -.
DR KEGG; chd:Calhy_2236; -.
DR eggNOG; COG0398; Bacteria.
DR HOGENOM; CLU_038944_8_2_9; -.
DR OrthoDB; 9812980at2; -.
DR Proteomes; UP000006890; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR015414; TMEM64.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR12677:SF59; TVP38_TMEM64 FAMILY INNER MEMBRANE PROTEIN YDJZ; 1.
DR PANTHER; PTHR12677; UNCHARACTERIZED; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU366058};
KW Membrane {ECO:0000256|RuleBase:RU366058};
KW Transmembrane {ECO:0000256|RuleBase:RU366058};
KW Transmembrane helix {ECO:0000256|RuleBase:RU366058}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 50..78
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 85..109
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 166..184
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 196..214
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT DOMAIN 69..186
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
SQ SEQUENCE 233 AA; 26635 MW; D315A95DDB53F86B CRC64;
MVEEIRIKDK IKLWIFIFIM VLSIFALVYA EKQHQLNPKY IKQYISHFGV WAPLVFLILY
SVKSFIIFIP AGVFMLAAGL SFGTLFGALI LIVGTLLSST IGFVFARYFG KDYVQKKLKN
TKFSNVGKKI AEKGFLIILL LRLVPILPYD AINYICGLSK IRYRDFILAT FIGTVPACFL
YAYLGENILR PFSTGFYLSL CLVIVISLTP VLFAKTIKEF LQNDKEEEDK HKI
//
