ID E4RQG9_LEAB4 Unreviewed; 1208 AA.
AC E4RQG9;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Peptidase M1 membrane alanine aminopeptidase domain-containing protein {ECO:0000259|Pfam:PF01433};
GN OrderedLocusNames=Lbys_2715 {ECO:0000313|EMBL:ADQ18377.1};
OS Leadbetterella byssophila (strain DSM 17132 / JCM 16389 / KACC 11308 / NBRC
OS 106382 / 4M15).
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Leadbetterella.
OX NCBI_TaxID=649349 {ECO:0000313|EMBL:ADQ18377.1, ECO:0000313|Proteomes:UP000007435};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17132;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Teshima H., Brettin T., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B.,
RA Pomrenke H.G., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Leadbetterella byssophila DSM 17132.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADQ18377.1, ECO:0000313|Proteomes:UP000007435}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17132 / JCM 16389 / KACC 11308 / NBRC 106382 / 4M15
RC {ECO:0000313|Proteomes:UP000007435};
RX PubMed=21475582; DOI=10.4056/sigs.1413518;
RA Abt B., Teshima H., Lucas S., Lapidus A., Del Rio T.G., Nolan M., Tice H.,
RA Cheng J.F., Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K.,
RA Pati A., Tapia R., Han C., Goodwin L., Chen A., Palaniappan K., Land M.,
RA Hauser L., Chang Y.J., Jeffries C.D., Rohde M., Goker M., Tindall B.J.,
RA Detter J.C., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Leadbetterella byssophila type strain
RT (4M15).";
RL Stand. Genomic Sci. 4:2-12(2011).
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DR EMBL; CP002305; ADQ18377.1; -; Genomic_DNA.
DR RefSeq; WP_013409411.1; NC_014655.1.
DR AlphaFoldDB; E4RQG9; -.
DR STRING; 649349.Lbys_2715; -.
DR KEGG; lby:Lbys_2715; -.
DR eggNOG; COG0308; Bacteria.
DR eggNOG; COG1277; Bacteria.
DR HOGENOM; CLU_007999_0_0_10; -.
DR OrthoDB; 100605at2; -.
DR Proteomes; UP000007435; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR InterPro; IPR014782; Peptidase_M1_dom.
DR InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR PANTHER; PTHR37305:SF1; ABC TRANSPORTER, MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR37305; INTEGRAL MEMBRANE PROTEIN-RELATED; 1.
DR Pfam; PF01433; Peptidase_M1; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007435};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 528..549
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 570..591
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 933..1075
FT /note="Peptidase M1 membrane alanine aminopeptidase"
FT /evidence="ECO:0000259|Pfam:PF01433"
SQ SEQUENCE 1208 AA; 139144 MW; 0F7D3082BD9E6435 CRC64;
MLRTIFTFET KRWLTQPTFY IYFAAFFGIG FLVMGSALGY FDALTVTSTS NTFYNSPLAV
NSLINGFSQL LNFIIPTVIG STVYRDYKYN MHTVLYSYPF TKWDYLVGKF LSGFFITVLV
SLAIGLSFIV ASVLPFANQD LMGPFRLWAF LQSYLIFVIP NIFFIGAIIF LLVTLTRNVY
IGFIFILILL ILQLIIGNLT ENMDDKFVAA LIEPYGEEAL SYVSKYWSID EQNYNNIPLD
KSILLNRLIW IGVGFLALVL TYTTFNFSHS PLTFGKKKLG EKVTKNNFQS VFKVKLPEVS
FDYSFAHYFK TSLNLAKIEF RSIVRNWIFI SIVAVLFLFV IIMGYTLGED LMGTKTYPVT
WKILSTISGQ FIFFSEILIF LFSGVLLNQA MSSRMDSLVD STPIPNWALL LSKFLALVGM
CLVLMFTAIV SGMLVQAYYG YYHFELILYF KQLLFFTMIN CLILIGMALF VQSLFKNYLL
GFMTLIVLLM LPSGLRKLGV ELPIFHFNSG TGLSYSDMNG FGSFRTHLIY KAYWLLFSGI
LYGLTLLFWR RGKFSGAMDR ISTAAGRLKL PIAAPLTLLL TAFIGLGYAI YREIAVNKPF
YTSKDQELRL VDFEKKYKKY QNTPQPRIVD VRVEMNIFPK ERNYDATGFF TLVNKTDKNI
DSLIIDYAKN LRNVQWDKPT SLILADSNLR FSIYKLAEPL APGDTVKAQF LVGNPRNTWF
QDESPVLENG TFINNRTLFP SIGYQEDNEI QDNDVRKKYG LKDKERMAFP SDLKARGNTY
ISNDADWINF EAIVSTSEDQ IAIAPGYLQR EWGDNGRKFY HYKMDQPIQN FYAFNSARYE
VKREKYKGVN LEIYYHKTHD YNIDRMIMSL KDGLDYFSEN FGPYQHKQVR ILEFPRTGGG
FAQSFPNTIP YSEAIGFIAW VDENKPNSVD YPYSITAHEL AHQWWAGQVI GANVKGATLL
SESMSEYSSL KVLEKKYGKF QMHKFLKDAL DNYLLGRAKE WKSENPLMYN ENQQYIHYNK
GSLVLYAMSD YLGEARFNAV LKDYIQKYRF QEPPYTTSEE FVALLKEATP DSLQYLIKDM
FETITLYNNK VDKASVKDLG KGKYQVDIDF QVSKYRTDNK GKRDYSGGIK DGKVQSLPLA
DYIELGIFGE KEKKGSYEYD KELYLKKYKI SKIKNKLSII VDEKPVEVGV DPYNKLIDID
SNDNRRSL
//
