ID E4RZ28_LEAB4 Unreviewed; 470 AA.
AC E4RZ28;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Glycoside hydrolase family 29 (Alpha-L-fucosidase) {ECO:0000313|EMBL:ADQ18247.1};
GN OrderedLocusNames=Lbys_2585 {ECO:0000313|EMBL:ADQ18247.1};
OS Leadbetterella byssophila (strain DSM 17132 / JCM 16389 / KACC 11308 / NBRC
OS 106382 / 4M15).
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Leadbetterella.
OX NCBI_TaxID=649349 {ECO:0000313|EMBL:ADQ18247.1, ECO:0000313|Proteomes:UP000007435};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17132;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Teshima H., Brettin T., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B.,
RA Pomrenke H.G., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Leadbetterella byssophila DSM 17132.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADQ18247.1, ECO:0000313|Proteomes:UP000007435}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17132 / JCM 16389 / KACC 11308 / NBRC 106382 / 4M15
RC {ECO:0000313|Proteomes:UP000007435};
RX PubMed=21475582; DOI=10.4056/sigs.1413518;
RA Abt B., Teshima H., Lucas S., Lapidus A., Del Rio T.G., Nolan M., Tice H.,
RA Cheng J.F., Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K.,
RA Pati A., Tapia R., Han C., Goodwin L., Chen A., Palaniappan K., Land M.,
RA Hauser L., Chang Y.J., Jeffries C.D., Rohde M., Goker M., Tindall B.J.,
RA Detter J.C., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Leadbetterella byssophila type strain
RT (4M15).";
RL Stand. Genomic Sci. 4:2-12(2011).
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
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DR EMBL; CP002305; ADQ18247.1; -; Genomic_DNA.
DR RefSeq; WP_013409285.1; NC_014655.1.
DR AlphaFoldDB; E4RZ28; -.
DR STRING; 649349.Lbys_2585; -.
DR CAZy; GH29; Glycoside Hydrolase Family 29.
DR KEGG; lby:Lbys_2585; -.
DR eggNOG; COG3669; Bacteria.
DR HOGENOM; CLU_002934_0_3_10; -.
DR OrthoDB; 107551at2; -.
DR Proteomes; UP000007435; Chromosome.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ADQ18247.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007435};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..470
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003187048"
FT SITE 308
FT /note="May be important for catalysis"
FT /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ SEQUENCE 470 AA; 55064 MW; 4A9192C4B70E1C6D CRC64;
MRICIYLLFF AFTLKAQNTL HPVSTSYTYP TDPLVAEKLE KWRDQKFGMI IHWGIYAVPG
IIESWSICNE DWIERDSTIR YDDYKRWYWS QSEKFNPIKF NPEQWASAAK EAGMKYLVFT
TKHHDGFSMF DTKWTDFKIT SGPFRNHPRA NVTQHVFEAF RKEGMMIGAY FSKPDWHSQY
FWWDKYATPD RNVNYDIRKH PWRWNKFKEF THGQINELTS EYGPVDILWL DGGWVRPRNT
VTEEVLSWGA PIPDFDQEID MPKVAQIARA NQPGILVVDR TVHGEFENYR TPEQGIPSTK
SEDPWESCIT LGGAWSYVPG DQFKSAEWAI KTLVEIVSKG GNLLLGVGPT PEGEFLPVQL
ERLKEIGKWL ERNGEGIYET RTVDQFKYEH FYFTRAKDQR RFAIRLNNEP LTEEVSWKGN
APKKGSKMFI LDGNIPVKWQ QEGELTRVFI PKKSLDKLAK DAAITFKFEQ
//
