ID E4SEF8_CALK2 Unreviewed; 595 AA.
AC E4SEF8;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Fumarate reductase/succinate dehydrogenase flavoprotein domain protein {ECO:0000313|EMBL:ADQ45445.1};
GN OrderedLocusNames=Calkro_0547 {ECO:0000313|EMBL:ADQ45445.1};
OS Caldicellulosiruptor kronotskyensis (strain DSM 18902 / VKM B-2412 / 2002).
OC Bacteria; Bacillota; Clostridia; Caldicellulosiruptorales;
OC Caldicellulosiruptoraceae; Caldicellulosiruptor.
OX NCBI_TaxID=632348 {ECO:0000313|EMBL:ADQ45445.1, ECO:0000313|Proteomes:UP000006835};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=2002;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N.,
RA Blumer-Schuette S.E., Kelly R.M., Woyke T.;
RT "Complete sequence of Caldicellulosiruptor kronotskyensis 2002.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADQ45445.1, ECO:0000313|Proteomes:UP000006835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18902 / VKM B-2412 / 2002
RC {ECO:0000313|Proteomes:UP000006835};
RX PubMed=21216991; DOI=10.1128/JB.01515-10;
RA Blumer-Schuette S.E., Ozdemir I., Mistry D., Lucas S., Lapidus A.,
RA Cheng J.F., Goodwin L.A., Pitluck S., Land M.L., Hauser L.J., Woyke T.,
RA Mikhailova N., Pati A., Kyrpides N.C., Ivanova N., Detter J.C.,
RA Walston-Davenport K., Han S., Adams M.W., Kelly R.M.;
RT "Complete genome sequences for the anaerobic, extremely thermophilic plant
RT biomass-degrading bacteria Caldicellulosiruptor hydrothermalis,
RT Caldicellulosiruptor kristjanssonii, Caldicellulosiruptor kronotskyensis,
RT Caldicellulosiruptor owensenis, and Caldicellulosiruptor lactoaceticus.";
RL J. Bacteriol. 193:1483-1484(2011).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; CP002330; ADQ45445.1; -; Genomic_DNA.
DR RefSeq; WP_013429595.1; NC_014720.1.
DR AlphaFoldDB; E4SEF8; -.
DR KEGG; ckn:Calkro_0547; -.
DR PATRIC; fig|632348.3.peg.581; -.
DR HOGENOM; CLU_014312_8_1_9; -.
DR OrthoDB; 9806724at2; -.
DR Proteomes; UP000006835; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR11632:SF82; FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PIRSF; PIRSF000171; SDHA_APRA_LASPO; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 6..426
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 482..584
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
SQ SEQUENCE 595 AA; 66320 MW; C8C73130CEC381CB CRC64;
MIYKTDILVV GGGGAGLRAA IAACEKAYEN KKSVKVILAV KGRLGSCGTT ALAYSDRMAF
HVTLPTTEPP GEDNWKYHAK DIYEIGGLVS DYDLAEILAK NSADAYFYLD SLGVPFVKEN
GVPVQFVTDG SIYARACFTG PDTAVQIEKA LIRKLGEMKD IEVLEDVMIS DLIVVNNKVC
GAIGFKENQN IIILAKAVVL ATGGAGSIYK SNVFPPRMTG DGYAMALRAG AQLVNMEFIQ
IGLSSPKTKL ACSGSIMRCV PRFVNEKGEE FLLNYPITYN DVFEKGATWP ISYEHKTCLI
DIAVFREIAR GGKVFLDFTQ NPKGFEFEHL REDLKQRYYK EIKNQIGSRK TPYERLCEIN
PQTVEWFLKR GIDLRNQMLE IAPSIQHFQG GVKIREKANT AISGLYACGE CAGGQHGANR
PGGNALLDTQ VFGKIAGESS FEFALNTSID EESIVCQANR LFESYKSYVA EDGIDLEKAI
SELNSVMDLY ASVVRYQAGL QKALMKIEEL KTRKVKPVEY EYLLELKNML LCAEAMVKSC
ILRDESRGPH LMFENYSDLW PKPRDERYNV YHVCRLNKET NQIEVFPMQP VKPKA
//
