ID   E4SK12_LACAR            Unreviewed;      1003 AA.
AC   E4SK12;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=Alpha-glucosidase {ECO:0000313|EMBL:ADQ58156.1};
GN   OrderedLocusNames=LA2_00795 {ECO:0000313|EMBL:ADQ58156.1};
OS   Lactobacillus amylovorus (strain GRL 1112).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=695560 {ECO:0000313|EMBL:ADQ58156.1, ECO:0000313|Proteomes:UP000007033};
RN   [1] {ECO:0000313|EMBL:ADQ58156.1, ECO:0000313|Proteomes:UP000007033}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GRL 1112 {ECO:0000313|EMBL:ADQ58156.1,
RC   ECO:0000313|Proteomes:UP000007033};
RX   PubMed=21131492; DOI=10.1128/JB.01365-10;
RA   Kant R., Paulin L., Alatalo E., de Vos W.M., Palva A.;
RT   "Genome sequence of Lactobacillus amylovorus GRL1112.";
RL   J. Bacteriol. 193:789-790(2011).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC       {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
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DR   EMBL; CP002338; ADQ58156.1; -; Genomic_DNA.
DR   RefSeq; WP_013436987.1; NC_014724.1.
DR   AlphaFoldDB; E4SK12; -.
DR   CAZy; GH31; Glycoside Hydrolase Family 31.
DR   GeneID; 66522938; -.
DR   KEGG; lam:LA2_00795; -.
DR   PATRIC; fig|695560.3.peg.156; -.
DR   HOGENOM; CLU_001337_1_0_9; -.
DR   Proteomes; UP000007033; Chromosome.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd00063; FN3; 1.
DR   CDD; cd14752; GH31_N; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 2.
DR   InterPro; IPR033403; DUF5110.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR048395; Glyco_hydro_31_C.
DR   InterPro; IPR000322; Glyco_hydro_31_TIM.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR22762; ALPHA-GLUCOSIDASE; 1.
DR   PANTHER; PTHR22762:SF54; BCDNA.GH04962; 1.
DR   Pfam; PF17137; DUF5110; 1.
DR   Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR   Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
DR   PROSITE; PS50853; FN3; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|RuleBase:RU361185};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361185}.
FT   DOMAIN          759..862
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
SQ   SEQUENCE   1003 AA;  113956 MW;  48BF60AAC32447CB CRC64;
     MTQNTQIERH QLGQLIGANK RDHYYELHYS TGEVARLYIL AEGIFRYFLD PAKNFDENHS
     SFVDLAQFDN SYFEKSKPKA TSDSLIIQSG NYQLIFQQKP AVMNIFDETL HRNRVMQLSP
     LELDQNQTTE ILKQHKNEFY FGGGMQNGYF SHKGKVIEIK RDKITGKGGV LSQIPFFWAN
     SGFGELRNTE STGSYDFGKT EADATILKHN TNVFDTFYLL GNSPKDILAK YYTLTGKPLM
     PPKYALGLGH IGNFLTTLWQ PGEAKERNAT VFEDGNYYTR TDNPEDSNGK ASLNGEEEYQ
     FSARAMVDRY EKQHFKLSWI VPNYEIQDVN PEAMASFSDY ASSRDVNAGV WSGDETPKTA
     PDTPFIQTTS SNPKTLKDDA IILRDNLKRK RPLIFSNTGI AGSQSRTILA FGDIGGNWEN
     IPTQVAGFLG SSLSGQPLIG SAVDGTAGGG NAQISIRDFE WKAFTPLLFN LDDQGKFSKT
     PFTYNSKMTQ INRAYLKLRE QLRTYMYTLI YCAQVGEPIM RPLFLEFPHE QINYTPQVGH
     EFMLGPNLLI SPIVNGREDG NGNSRKDNLY LPNHRTMWVD LFDGKKYLGG RVYNKQSYPS
     WHLPVFVRGG SIFDLGERNY VLYPQGHSKM VTYDDNGYND YSRNHVSTQI SSDLEASKLT
     ITIDPTQGDF STFQTENTTN LNIMCDGYPD GLTVKINDQV INMQEYGTVD TFAHAKEGFF
     FNTNYSWMPE FDQYQEKKQT ALQIKLAKRD ITDSKIEITI RNFRYGNETL VHAITDSLLR
     SPKQPTVDPD KISSHSLTVV WPQLTDKVQI EVNGILHDGI DGSSFTFHEL VPNTRYTLRL
     RYVAGNKVSE WSDPFGAITK PDPMNYAINN IKVTSNLTSQ KDHPLEYLTD LKLASEWKTV
     NGVSEDEPLE LNFKFNQLEH LSRMVWVPRK IDHQGDPVEV SVETSTDGVN FKPYGERLTW
     KSDSKNKVVG LRDVAVKAIR LKVYKSSGPF IASKEIIFFR EKK
//