ID   E4SK50_LACAR            Unreviewed;       449 AA.
AC   E4SK50;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Glycosyltransferase {ECO:0000313|EMBL:ADQ58194.1};
GN   OrderedLocusNames=LA2_00985 {ECO:0000313|EMBL:ADQ58194.1};
OS   Lactobacillus amylovorus (strain GRL 1112).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=695560 {ECO:0000313|EMBL:ADQ58194.1, ECO:0000313|Proteomes:UP000007033};
RN   [1] {ECO:0000313|EMBL:ADQ58194.1, ECO:0000313|Proteomes:UP000007033}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GRL 1112 {ECO:0000313|EMBL:ADQ58194.1,
RC   ECO:0000313|Proteomes:UP000007033};
RX   PubMed=21131492; DOI=10.1128/JB.01365-10;
RA   Kant R., Paulin L., Alatalo E., de Vos W.M., Palva A.;
RT   "Genome sequence of Lactobacillus amylovorus GRL1112.";
RL   J. Bacteriol. 193:789-790(2011).
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC       {ECO:0000256|ARBA:ARBA00006739}.
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DR   EMBL; CP002338; ADQ58194.1; -; Genomic_DNA.
DR   RefSeq; WP_013437024.1; NC_014724.1.
DR   AlphaFoldDB; E4SK50; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   KEGG; lam:LA2_00985; -.
DR   PATRIC; fig|695560.3.peg.194; -.
DR   HOGENOM; CLU_603805_0_0_9; -.
DR   Proteomes; UP000007033; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd06423; CESA_like; 1.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR017542; Glycosyltfrase_exosort_G_assoc.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   NCBIfam; TIGR03111; glyc2_xrt_Gpos1; 1.
DR   PANTHER; PTHR43630; POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE; 1.
DR   PANTHER; PTHR43630:SF1; POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE; 1.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        323..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        347..366
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        386..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          56..187
FT                   /note="Glycosyltransferase 2-like"
FT                   /evidence="ECO:0000259|Pfam:PF00535"
SQ   SEQUENCE   449 AA;  52449 MW;  E290B57634D57D35 CRC64;
     MYITNLIIQS GFWITWLLIP IIYELIPAII GFFSLQVAKQ HFKHLKPISK YPYITLIVPV
     YNSEDSLFNC IKSIETSSYP DEKIKVLIAD NQSKDNSYQE YLRARNIFHK LNMQWLSTDQ
     GKAKALNAAI YNSIGKYVIH IDSDGVLQED ALLYIVTDFE NDSSIDALTG TILTRISLIK
     KTKNKFLKFI RENEYMEYCQ SFLAGRAVES QGNRLFTMSG AFSAFRRNKL LGTDLYNIET
     IGEDIDMTFQ IRYQLKGRAL LCPLAIFYVS PLDNINKLYT QRQRWLRGEL ETLHLFFENR
     SIGISTFFKN FVVRRLVMDH TILLLRVIWT FAFVLLILLG YSSNVVITSF VLLYLLYLFI
     LLLNFLSIQS FLKRFSSDRK YYLSKFYILL SLPIYYFACS FIQVIGIINA MTTPAAWTTK
     NITQEFSDCK KVIEKDWMAN RYGKRKRKL
//